Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 9/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TET3 | O43151 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.39 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434463 | 0.89 | SLC40A1 (0.67) | SLC40A1KDM4EHPGDTP53KMT2A | |
| SCHEMBL18434695 | 0.84 | SLC40A1 (0.63) | SLC40A1KDM4EL3MBTL1 | |
| SCHEMBL11995690 | 0.80 | SLC40A1 (0.80) | SLC40A1 | |
| SCHEMBL18434817 | 0.76 | SLC40A1 (0.57) | SLC40A1KDM4EL3MBTL1 | |
| SCHEMBL18434471 | 0.74 | SLC40A1 (0.66) | SLC40A1KDM4EL3MBTL1HPGDALDH1A1 | |
| SCHEMBL18434678 | 0.71 | SLC40A1 (0.57) | SLC40A1KDM4EL3MBTL1HPGDALDH1A1 | |
| SCHEMBL11997084 | 0.71 | SLC40A1 (0.68) | SLC40A1 | |
| SCHEMBL18434466 | 0.70 | SLC40A1 (0.69) | SLC40A1KDM4EHPGDTP53KMT2A | |
| SCHEMBL11995689 | 0.69 | SLC40A1 (1.00) | SLC40A1 | |
| SCHEMBL18434682 | 0.68 | SLC40A1 (0.50) | SLC40A1KDM4EL3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |