Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 16/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.34 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.34 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11973787 | 0.79 | SLC40A1 (0.86) | SLC40A1 | |
| SCHEMBL18434464 | 0.79 | SLC40A1 (0.55) | SLC40A1ROCK1IKBKBBMPR1BBMPR1A | |
| SCHEMBL11973348 | 0.74 | SLC40A1 (0.80) | SLC40A1 | |
| SCHEMBL18434808 | 0.73 | SLC40A1 (0.51) | SLC40A1BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL11973548 | 0.71 | SLC40A1 (1.00) | SLC40A1 | |
| SCHEMBL18434709 | 0.71 | SLC40A1 (0.65) | SLC40A1 | |
| SCHEMBL11997135 | 0.70 | SLC40A1 (0.68) | SLC40A1 | |
| SCHEMBL2367123 | 0.67 | PARP1 (0.53) | SLC40A1ROCK1IKBKB | |
| SCHEMBL11995693 | 0.65 | SLC40A1 (1.00) | SLC40A1 | |
| SCHEMBL18434807 | 0.65 | SLC40A1 (0.70) | SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |