Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 12/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.36 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.36 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434808 | 0.94 | SLC40A1 (0.51) | SLC40A1BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL18434709 | 0.92 | SLC40A1 (0.65) | SLC40A1CCR1CCR8L3MBTL1 | |
| SCHEMBL18434807 | 0.83 | SLC40A1 (0.70) | SLC40A1 | |
| SCHEMBL18434474 | 0.80 | SLC40A1 (0.71) | SLC40A1 | |
| SCHEMBL18434683 | 0.80 | SLC40A1 (0.62) | SLC40A1CCR1CCR8L3MBTL1 | |
| SCHEMBL11973787 | 0.79 | SLC40A1 (0.86) | SLC40A1 | |
| SCHEMBL18434467 | 0.79 | SLC40A1 (0.55) | SLC40A1ROCK1IKBKBBMPR1BBMPR1A | |
| SCHEMBL18434845 | 0.78 | SLC40A1 (0.58) | SLC40A1CCR1CCR8L3MBTL1 | |
| SCHEMBL18434461 | 0.76 | SLC40A1 (0.69) | SLC40A1 | |
| SCHEMBL18434412 | 0.75 | SLC40A1 (0.55) | SLC40A1CCR1CCR8L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |