Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 5/20 | 0.51 |
| ▸ | PRKCZ | Q05513 | 5/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.37 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.37 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434464 | 0.94 | SLC40A1 (0.55) | SLC40A1PRKCZBMPR1BBMPR1AACVRL1 | |
| SCHEMBL18434709 | 0.89 | SLC40A1 (0.65) | SLC40A1 | |
| SCHEMBL18434474 | 0.84 | SLC40A1 (0.71) | SLC40A1 | |
| SCHEMBL11973348 | 0.80 | SLC40A1 (0.80) | SLC40A1 | |
| SCHEMBL18434807 | 0.80 | SLC40A1 (0.70) | SLC40A1 | |
| SCHEMBL18434683 | 0.78 | SLC40A1 (0.62) | SLC40A1 | |
| SCHEMBL18434845 | 0.77 | SLC40A1 (0.58) | SLC40A1 | |
| SCHEMBL11973787 | 0.74 | SLC40A1 (0.86) | SLC40A1 | |
| SCHEMBL18434461 | 0.74 | SLC40A1 (0.69) | SLC40A1 | |
| SCHEMBL18434412 | 0.74 | SLC40A1 (0.55) | SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |