Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 12/20 | 0.58 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | COMT | P21964 | 2/20 | 0.40 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TOP1 | P11387 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434660 | 0.83 | SLC40A1 (0.53) | SLC40A1COMTKDM4EMEN1ALDH1A1 | |
| SCHEMBL18434678 | 0.77 | SLC40A1 (0.57) | SLC40A1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL18434326 | 0.75 | SLC40A1 (0.60) | SLC40A1KIF11COMTNFKBIARELA | |
| SCHEMBL11973254 | 0.73 | SLC40A1 (1.00) | SLC40A1NFKBIARELA | |
| SCHEMBL18434688 | 0.69 | SLC40A1 (0.53) | SLC40A1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL18434682 | 0.65 | SLC40A1 (0.50) | SLC40A1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL18434816 | 0.65 | SLC40A1 (0.55) | SLC40A1TDP1GSK3B | |
| SCHEMBL18434695 | 0.65 | SLC40A1 (0.63) | SLC40A1KDM4EL3MBTL1 | |
| SCHEMBL18434454 | 0.65 | SLC40A1 (0.53) | SLC40A1NFKBIARELAKDM4EMEN1 | |
| SCHEMBL18434854 | 0.64 | SLC40A1 (0.59) | SLC40A1KDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |