Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 12/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434660 | 0.85 | SLC40A1 (0.53) | SLC40A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL18434854 | 0.78 | SLC40A1 (0.59) | SLC40A1HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18434505 | 0.76 | SLC40A1 (0.60) | SLC40A1MAPT | |
| SCHEMBL18434791 | 0.73 | SLC40A1 (0.52) | SLC40A1HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18434842 | 0.73 | SLC40A1 (0.52) | SLC40A1HSP90AA1 | |
| SCHEMBL18434712 | 0.71 | SLC40A1 (0.64) | SLC40A1MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL12475058 | 0.71 | SLC40A1 (0.55) | SLC40A1HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18434820 | 0.71 | SLC40A1 (0.49) | SLC40A1MEN1KMT2ASMN1; SMN2USP2 | |
| SCHEMBL18434621 | 0.71 | SLC40A1 (0.65) | SLC40A1TDP1 | |
| SCHEMBL18434816 | 0.70 | SLC40A1 (0.55) | SLC40A1TDP1CYP1A2ALOX15HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |