Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.39 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.39 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434505 | 0.89 | SLC40A1 (0.60) | SLC40A1MAPTMAPK1METAP1TSHR | |
| SCHEMBL18434820 | 0.83 | SLC40A1 (0.49) | SLC40A1SMN1; SMN2MEN1CASP1KMT2A | |
| SCHEMBL18434621 | 0.83 | SLC40A1 (0.65) | SLC40A1TDP1 | |
| SCHEMBL18434688 | 0.78 | SLC40A1 (0.53) | SLC40A1MAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL18434660 | 0.78 | SLC40A1 (0.53) | SLC40A1MAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL18434682 | 0.77 | SLC40A1 (0.50) | SLC40A1MAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL18434448 | 0.76 | SLC40A1 (0.61) | SLC40A1MAPTALDH1A1KDM4EMAPK1 | |
| SCHEMBL18434692 | 0.75 | SLC40A1 (0.67) | SLC40A1KDM4E | |
| SCHEMBL18434849 | 0.74 | SLC40A1 (0.60) | SLC40A1MAPTALDH1A1KDM4EMAPK1 | |
| SCHEMBL11973802 | 0.74 | SLC40A1 (1.00) | SLC40A1MAPTALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |