Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 14/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434326 | 0.87 | SLC40A1 (0.60) | SLC40A1L3MBTL1KIF11NFKBIARELA | |
| SCHEMBL18434653 | 0.86 | SLC40A1 (0.46) | SLC40A1CCR1CCR8KIF11NFKBIA | |
| SCHEMBL18434478 | 0.84 | SLC40A1 (0.63) | SLC40A1KIF11NFKBIARELA | |
| SCHEMBL18434845 | 0.82 | SLC40A1 (0.58) | SLC40A1L3MBTL1CCR1CCR8KDM4E | |
| SCHEMBL18434412 | 0.82 | SLC40A1 (0.55) | SLC40A1L3MBTL1CCR1CCR8KDM4E | |
| SCHEMBL18434680 | 0.81 | SLC40A1 (0.58) | SLC40A1L3MBTL1CCR1CCR8KDM4E | |
| SCHEMBL18434806 | 0.80 | SLC40A1 (0.58) | SLC40A1L3MBTL1CCR1CCR8KDM4E | |
| SCHEMBL18434673 | 0.80 | SLC40A1 (0.44) | SLC40A1L3MBTL1CCR1CCR8KDM4E | |
| SCHEMBL18434486 | 0.80 | SLC40A1 (0.61) | SLC40A1L3MBTL1CCR1CCR8NFKBIA | |
| SCHEMBL18434683 | 0.78 | SLC40A1 (0.62) | SLC40A1L3MBTL1CCR1CCR8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |