Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 9/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434326 | 0.87 | SLC40A1 (0.60) | SLC40A1KIF11NFKBIARELATOP1 | |
| SCHEMBL18434496 | 0.86 | SLC40A1 (0.61) | SLC40A1CCR1CCR8KIF11NFKBIA | |
| SCHEMBL18434478 | 0.86 | SLC40A1 (0.63) | SLC40A1KIF11NFKBIARELACCNB2 | |
| SCHEMBL11997089 | 0.76 | SLC40A1 (0.78) | SLC40A1NFKBIARELA | |
| SCHEMBL18434486 | 0.75 | SLC40A1 (0.61) | SLC40A1CCR1CCR8NFKBIARELA | |
| SCHEMBL18434406 | 0.74 | SLC40A1 (0.58) | SLC40A1KIF11KDM4E | |
| SCHEMBL18434481 | 0.73 | SLC40A1 (0.60) | SLC40A1CCR1CCR8KIF11NFKBIA | |
| SCHEMBL18434664 | 0.69 | SLC40A1 (0.55) | SLC40A1KDM4E | |
| SCHEMBL18434845 | 0.68 | SLC40A1 (0.58) | SLC40A1CCR1CCR8KDM4ESLC6A2 | |
| SCHEMBL18434673 | 0.68 | SLC40A1 (0.44) | SLC40A1CCR1CCR8KDM4ESLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |