Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 12/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434682 | 0.71 | SLC40A1 (0.50) | ALDH1A1METAP2SLC40A1KDM4EMAPT | |
| SCHEMBL18434633 | 0.66 | KDM4E (0.36) | ALDH1A1SLC40A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL18434678 | 0.65 | SLC40A1 (0.57) | ALDH1A1METAP2SLC40A1KDM4EMAPT | |
| SCHEMBL18434821 | 0.64 | SLC40A1 (0.64) | SLC40A1KDM4EMAPTL3MBTL1HTT | |
| SCHEMBL18434854 | 0.62 | SLC40A1 (0.59) | ALDH1A1SLC40A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL18434817 | 0.61 | SLC40A1 (0.57) | METAP2SLC40A1KDM4EL3MBTL1 | |
| SCHEMBL18434471 | 0.61 | SLC40A1 (0.66) | ALDH1A1METAP2SLC40A1KDM4EMAPT | |
| SCHEMBL18434695 | 0.58 | SLC40A1 (0.63) | SLC40A1KDM4EL3MBTL1CCR1CCR8 | |
| SCHEMBL18434689 | 0.58 | SLC40A1 (0.52) | ALDH1A1METAP2SLC40A1KDM4EMAPT | |
| SCHEMBL20665823 | 0.55 | ALDH1A1 (0.61) | ALDH1A1METAP2KDM4EMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |