Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 15/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434402 | 0.81 | SLC40A1 (0.60) | SLC40A1MAPT | |
| SCHEMBL11973691 | 0.80 | SLC40A1 (0.55) | SLC40A1 | |
| SCHEMBL18434792 | 0.80 | SLC40A1 (0.55) | SLC40A1KDM4ELMNATP53MAPT | |
| SCHEMBL18434832 | 0.79 | SLC40A1 (0.58) | SLC40A1 | |
| SCHEMBL18434654 | 0.79 | SLC40A1 (0.58) | SLC40A1LMNAMAPTTSHR | |
| SCHEMBL18434662 | 0.79 | SLC40A1 (0.58) | SLC40A1 | |
| SCHEMBL11973237 | 0.79 | SLC40A1 (0.49) | SLC40A1 | |
| SCHEMBL11973717 | 0.78 | SLC40A1 (0.47) | SLC40A1KDM4E | |
| SCHEMBL11973515 | 0.77 | SLC40A1 (0.61) | SLC40A1KDM4E | |
| SCHEMBL11973273 | 0.77 | SLC40A1 (0.63) | SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |