Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 15/20 | 0.58 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434844 | 0.82 | SLC40A1 (0.63) | SLC40A1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL18434846 | 0.80 | SLC40A1 (0.39) | SLC40A1 | |
| SCHEMBL11973691 | 0.80 | SLC40A1 (0.55) | SLC40A1KEAP1NFE2L2 | |
| SCHEMBL18434792 | 0.80 | SLC40A1 (0.55) | SLC40A1HTR1AMEN1KMT2A | |
| SCHEMBL11973273 | 0.79 | SLC40A1 (0.63) | SLC40A1 | |
| SCHEMBL18434654 | 0.79 | SLC40A1 (0.58) | SLC40A1MEN1KMT2A | |
| SCHEMBL18434626 | 0.79 | SLC40A1 (0.41) | SLC40A1 | |
| SCHEMBL18434662 | 0.79 | SLC40A1 (0.58) | SLC40A1 | |
| SCHEMBL11973710 | 0.77 | SLC40A1 (0.63) | SLC40A1 | |
| SCHEMBL18434785 | 0.76 | SLC40A1 (0.58) | SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |