Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 16/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434654 | 0.86 | SLC40A1 (0.58) | SLC40A1ALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL18434626 | 0.81 | SLC40A1 (0.41) | SLC40A1MAPT | |
| SCHEMBL11973237 | 0.78 | SLC40A1 (0.49) | SLC40A1 | |
| SCHEMBL11973691 | 0.77 | SLC40A1 (0.55) | SLC40A1 | |
| SCHEMBL18434792 | 0.77 | SLC40A1 (0.55) | SLC40A1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL18434662 | 0.76 | SLC40A1 (0.58) | SLC40A1 | |
| SCHEMBL18434832 | 0.76 | SLC40A1 (0.58) | SLC40A1 | |
| SCHEMBL18434399 | 0.75 | SLC40A1 (0.57) | SLC40A1ALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL11973258 | 0.75 | SLC40A1 (1.00) | SLC40A1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL18434844 | 0.74 | SLC40A1 (0.63) | SLC40A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |