Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 5/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434490 | 0.67 | SLC40A1 (0.52) | SLC40A1TDP1PIM1PIM2KDM4E | |
| SCHEMBL11973330 | 0.67 | SLC40A1 (1.00) | SLC40A1TDP1KDM4EMEN1ALDH1A1 | |
| SCHEMBL29697799 | 0.60 | KDM4E (0.34) | KDM4EMEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL29533844 | 0.59 | CCR1 (0.43) | SLC40A1TDP1PIM1PIM2KDM4E | |
| SCHEMBL557084 | 0.59 | CCR1 (0.43) | SLC40A1TDP1PIM1PIM2KDM4E | |
| SCHEMBL29697793 | 0.59 | GPR3 (0.32) | — | |
| SCHEMBL15220201 | 0.58 | CDC25B (0.36) | TDP1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL22970624 | 0.58 | SLC40A1 (0.46) | SLC40A1TDP1PIM1PIM2KDM4E | |
| SCHEMBL2116332 | 0.57 | PIM1 (0.44) | SLC40A1TDP1PIM1PIM2KDM4E | |
| SCHEMBL11973479 | 0.57 | SLC40A1 (1.00) | SLC40A1TDP1PIM1NFKBIARELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |