Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 8/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.38 |
| ▸ | NCF1 | P14598 | 2/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434500 | 0.87 | SLC40A1 (0.63) | SLC40A1CYP2C19NCF1KAT2BSLC2A1 | |
| SCHEMBL18434832 | 0.82 | SLC40A1 (0.58) | SLC40A1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL11972937 | 0.78 | SLC40A1 (1.00) | SLC40A1KDM4EALDH1A1 | |
| SCHEMBL18434654 | 0.77 | SLC40A1 (0.58) | SLC40A1ALDH1A1POLB | |
| SCHEMBL18434626 | 0.75 | SLC40A1 (0.41) | SLC40A1KDM4E | |
| SCHEMBL18434402 | 0.74 | SLC40A1 (0.60) | SLC40A1ALDH1A1 | |
| SCHEMBL18434697 | 0.74 | SLC40A1 (0.67) | SLC40A1KDM4EALDH1A1RAD52 | |
| SCHEMBL18434846 | 0.73 | SLC40A1 (0.39) | SLC40A1 | |
| SCHEMBL11973691 | 0.73 | SLC40A1 (0.55) | SLC40A1NCF1 | |
| SCHEMBL18434792 | 0.73 | SLC40A1 (0.55) | SLC40A1HTR1AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |