Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 13/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434850 | 0.95 | SLC40A1 (0.70) | SLC40A1ALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL18434773 | 0.88 | SLC40A1 (0.59) | SLC40A1 | |
| SCHEMBL18434473 | 0.88 | SLC40A1 (0.68) | SLC40A1ALDH1A1NPSR1 | |
| SCHEMBL11973325 | 0.81 | SLC40A1 (1.00) | SLC40A1 | |
| SCHEMBL18434461 | 0.80 | SLC40A1 (0.69) | SLC40A1 | |
| SCHEMBL18434807 | 0.79 | SLC40A1 (0.70) | SLC40A1 | |
| SCHEMBL18434694 | 0.78 | SLC40A1 (0.65) | SLC40A1 | |
| SCHEMBL18434474 | 0.77 | SLC40A1 (0.71) | SLC40A1 | |
| SCHEMBL11973455 | 0.77 | SLC40A1 (1.00) | SLC40A1 | |
| SCHEMBL18434677 | 0.75 | SLC40A1 (0.68) | SLC40A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |