Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 17/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11973352 | 0.83 | SLC40A1 (0.47) | SLC40A1KDM4EL3MBTL1 | |
| SCHEMBL18434773 | 0.81 | SLC40A1 (0.59) | SLC40A1KDM4EL3MBTL1 | |
| SCHEMBL18434466 | 0.80 | SLC40A1 (0.69) | SLC40A1KDM4E | |
| SCHEMBL18434461 | 0.80 | SLC40A1 (0.69) | SLC40A1 | |
| SCHEMBL18434677 | 0.80 | SLC40A1 (0.68) | SLC40A1KDM4EL3MBTL1 | |
| SCHEMBL18434473 | 0.79 | SLC40A1 (0.68) | SLC40A1KDM4EL3MBTL1 | |
| SCHEMBL11995688 | 0.79 | SLC40A1 (1.00) | SLC40A1 | |
| SCHEMBL18434807 | 0.78 | SLC40A1 (0.70) | SLC40A1 | |
| SCHEMBL18434853 | 0.78 | SLC40A1 (0.69) | SLC40A1 | |
| SCHEMBL18434845 | 0.78 | SLC40A1 (0.58) | SLC40A1KDM4ECCR1CCR8L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |