Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 16/20 | 0.59 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434473 | 0.89 | SLC40A1 (0.68) | SLC40A1RIPK1KDM4EL3MBTL1METAP2 | |
| SCHEMBL18434853 | 0.88 | SLC40A1 (0.69) | SLC40A1 | |
| SCHEMBL18434850 | 0.85 | SLC40A1 (0.70) | SLC40A1 | |
| SCHEMBL11973270 | 0.83 | SLC40A1 (0.83) | SLC40A1 | |
| SCHEMBL18434841 | 0.82 | SLC40A1 (0.52) | SLC40A1KDM4EL3MBTL1METAP2LMNA | |
| SCHEMBL18434694 | 0.81 | SLC40A1 (0.65) | SLC40A1KDM4EL3MBTL1 | |
| SCHEMBL18434817 | 0.80 | SLC40A1 (0.57) | SLC40A1RIPK1KDM4EL3MBTL1METAP2 | |
| SCHEMBL18434461 | 0.77 | SLC40A1 (0.69) | SLC40A1 | |
| SCHEMBL18434483 | 0.76 | SLC40A1 (0.50) | SLC40A1RIPK1 | |
| SCHEMBL18434466 | 0.76 | SLC40A1 (0.69) | SLC40A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |