SCHEMBL18436346

SCHEMBL18436346

FCc1cc(CBr)cc(CBr)c1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL331501 0.83 TRPA1 (0.47) TRPA1ALDH1A1TSHR
SCHEMBL3526008 0.78 TRPA1 (0.48) TRPA1ALDH1A1TSHR
SCHEMBL2702074 0.75 TRPA1 (0.50) TRPA1ALDH1A1TSHR
SCHEMBL30536364 0.75 IDO1 (0.39) TSHR
SCHEMBL19002957 0.73 TRPA1 (0.40) TRPA1ALDH1A1TSHR
SCHEMBL2327331 0.73 TRPA1 (0.31) TRPA1ALDH1A1TSHR
SCHEMBL642402 0.71 IDO1 (0.40) TRPA1ALDH1A1TSHR
SCHEMBL17043177 0.69
SCHEMBL19908902 0.69 TRPA1 (0.43) TRPA1ALDH1A1TSHR
SCHEMBL23654211 0.69 LOXL2 (0.36) TRPA1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3124490-A1 HIGH STABILITY POLYIONIC LIQUID SALTS Sigma-Aldrich Co. LLC (US) 2017-02-01 EP disclosed