SCHEMBL331501

SCHEMBL331501

BrCc1cc(CBr)cc(CBr)c1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.47
ALDH1A1 P00352 1/20 0.47
TSHR P16473 1/20 0.47
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19002957 0.89 TRPA1 (0.40) TRPA1ALDH1A1TSHR
SCHEMBL642402 0.86 IDO1 (0.40) TRPA1ALDH1A1TSHR
SCHEMBL10064215 0.83 TRPA1 (0.36) TRPA1ALDH1A1TSHR
SCHEMBL625710 0.83 TSHR (0.41) TRPA1ALDH1A1TSHR
SCHEMBL1229742 0.83 ACHE (0.48) TRPA1ALDH1A1TSHRCES2CES1
SCHEMBL23654211 0.83 LOXL2 (0.36) TRPA1ALDH1A1TSHR
SCHEMBL15574021 0.83 TRPA1 (0.36) TRPA1ALDH1A1TSHR
SCHEMBL18640647 0.83 PTGS2 (0.44) TRPA1ALDH1A1TSHR
SCHEMBL20715836 0.83 TRPA1 (0.36) TRPA1ALDH1A1TSHR
SCHEMBL29482741 0.83 TRPA1 (0.36) TRPA1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1510 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137791-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR PD-L1 Bicyclerd Limited (GB) 2026-05-21 US claimed
EP-4745151-A1 FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) 2026-05-20 EP claimed
CN-122037144-A Porphyrin-based super-crosslinked polymer catalyst modified by quaternary phosphonium salt ionic liquid and application thereof 南京工业大学 2026-05-15 CN claimed
CN-122004208-A Application of quaternized copolymer in preparation of pesticide slow-release agent and pesticide slow-release agent 浙江农林大学 2026-05-12 CN claimed
US-12590181-B2 Hydrophobically-modified associative thickener polymers process for the preparation and uses thereof HERCULES LLC (US) 2026-03-31 US claimed
EP-3463630-B1 PROCESS FOR THE PRODUCTION OF SOLVENT STABLE POLYMERIC MEMBRANES IP2IPO INNOVATIONS LTD (GB) 2026-02-25 EP claimed
US-12551567-B2 Bicyclic peptide ligands specific for PD-L1 Bicyclerd Limited (GB) 2026-02-17 US claimed
US-12552837-B2 Bicyclic peptide ligands with detectable moieties and uses thereof Bicyclerd Limited (GB) 2026-02-17 US claimed
EP-4676633-A1 DUAL-LAYER HOLLOW FIBRE MEMBRANE Divigas Pte Ltd (SG) 2026-01-14 EP claimed
US-12491253-B2 Bicyclic peptide ligands specific for MT1-MMP Bicyclerd Limited (GB) 2025-12-09 US claimed
CN-103943805-B Lithium rechargeable battery and barrier film thereof NINGDE AMPEREX TECHNOLOGY LTD. (CN) 2016-04-06 CN claimed
CN-103657610-B Porous polymer adsorbent for selectively adsorbing carbon dioxide and preparation method thereof NANJING TECH UNIVERSITY (CN) 2016-01-06 CN claimed
US-20140330031-A1 RESIST FOR ELECTRON BEAM AND OPTICAL LITHOGRAPHY COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-11-06 US claimed
CN-103943805-A Lithium ion secondary battery and diaphragm thereof NINGDE AMPEREX TECHNOLOGY LTD 2014-07-23 CN claimed
WO-2013084247-A1 RESIST FOR ELECTRON BEAM AND OPTICAL LITHOGRAPHY COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-06-13 WO claimed
US-6221991-B1 STAR POLYMER FMC CORPORATION 2001-04-24 US claimed
US-5900464-A USING AN ORGANOMETALLIC COMPOUND AS PROMOTER FMC CORPORATION (US) 1999-05-04 US claimed
EP-0620500-A2 Resist and pattern formation using the same HITACHI, LTD. (JP) 1994-10-19 EP claimed
EP-0456317-B1 CATALYST COMPOSITIONS AND POLYMERIZATION PROCESS, HEXAKISPHOSPHINES AND HEXAHALO COMPOUNDS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-08-25 EP claimed
EP-0456317-A1 Catalyst compositions and polymerization process, hexakisphosphines and hexahalo compounds SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-11-13 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552837-B2 Bicyclic peptide ligands with detectable moieties and uses thereof SSTR2, FPR1, NPR1 TRPA1 3657/4885ALDH1A1 4302/4885TSHR 147/4885
US-12551567-B2 Bicyclic peptide ligands specific for PD-L1 PDCD1LG2, CD274, PDCD1 TRPA1 4576/4885ALDH1A1 4526/4885TSHR 935/4885
US-12590181-B2 Hydrophobically-modified associative thickener polymers process for the preparation and uses thereof PHOSPHO1, H1-10, H1-0 TRPA1 553/4885ALDH1A1 4014/4885TSHR 3461/4885
US-20260137791-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR PD-L1 PDCD1LG2, CD274, PDCD1 TRPA1 4657/4885ALDH1A1 3312/4885TSHR 931/4885
US-12491253-B2 Bicyclic peptide ligands specific for MT1-MMP MMEL1, MMP3, TIMP3 TRPA1 4166/4885ALDH1A1 2057/4885TSHR 3421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.