Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.43 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.43 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18773562 | 0.93 | CYP2C19 (0.53) | CYP2C19APPBACE1SMN1; SMN2KDM4E | |
| SCHEMBL9607896 | 0.93 | THRB (0.43) | CYP2C19APPKDM4ECYP2D6CYP2C9 | |
| SCHEMBL18472253 | 0.92 | CYP2C19 (0.51) | CYP2C19APPBACE1SMN1; SMN2KDM4E | |
| SCHEMBL18966013 | 0.89 | LMNA (0.45) | CYP2C19APPBACE1SMN1; SMN2KDM4E | |
| SCHEMBL20342961 | 0.88 | APP (0.46) | CYP2C19APPCYP2D6CYP2C9THRB | |
| SCHEMBL18699638 | 0.88 | PTGS1 (0.43) | CYP2C19APPCYP1A2CYP2C9AKR1C3 | |
| SCHEMBL9607850 | 0.87 | THRB (0.43) | CYP2C19APPCYP2D6CYP2C9AKR1C3 | |
| SCHEMBL18432923 | 0.86 | BACE1 (0.45) | CYP2C19APPBACE1SMN1; SMN2KDM4E | |
| SCHEMBL22600356 | 0.86 | ELANE (0.41) | CYP2C19APPBACE1CYP2C9AKR1C3 | |
| SCHEMBL20343004 | 0.86 | THRB (0.45) | CYP2C19APPSMN1; SMN2KDM4ECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489329-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2022-01-12 | — | — | EP | disclosed |
| EP-3848436-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2021-07-14 | — | — | EP | disclosed |
| EP-3839620-A1 | DEVICE FOR THE REGULATION OF LIGHT TRANSMISSION | Merck Patent GmbH (DE) | 2021-06-23 | — | — | EP | disclosed |
| EP-3604481-B1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2021-05-26 | — | — | EP | disclosed |
| EP-3248060-B1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2020-09-02 | — | — | EP | disclosed |
| EP-3677659-A1 | LIQUID CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2020-07-08 | — | — | EP | disclosed |
| EP-2881383-B1 | Mixing device and its use | MERCK PATENT GMBH (DE) | 2020-06-24 | — | — | EP | disclosed |
| EP-2918658-B1 | Liquid crystalline media with homeotropic alignment | MERCK PATENT GMBH (DE) | 2020-05-13 | — | — | EP | disclosed |
| EP-3215892-B1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2020-03-18 | — | — | EP | disclosed |
| EP-2931836-B1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2020-03-18 | — | — | EP | disclosed |
| EP-3387089-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2019-10-02 | — | — | EP | disclosed |
| EP-3292181-B1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2019-09-11 | — | — | EP | disclosed |
| EP-2921545-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2019-08-21 | — | — | EP | disclosed |
| EP-3489329-A1 | LIQUID CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2019-05-29 | — | — | EP | disclosed |
| EP-3067406-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-04-24 | — | — | EP | disclosed |
| EP-3298105-B1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2019-03-20 | — | — | EP | disclosed |
| EP-2985334-B1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-06-20 | — | — | EP | disclosed |
| EP-2818531-B1 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2017-07-26 | — | — | EP | disclosed |
| EP-3127991-A1 | LIQUID CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2017-02-08 | — | — | EP | disclosed |
| EP-2922933-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2017-02-01 | — | — | EP | disclosed |