Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 4/20 | 0.32 |
| ▸ | LAP3 | P28838 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21336647 | 0.82 | KDM1A (0.36) | HRH4KDM1ASRCCCNA2CDK2 | |
| SCHEMBL21336936 | 0.81 | PDE9A (0.34) | HRH4ACP1KDM1A | |
| SCHEMBL18436916 | 0.81 | DPP4 (0.34) | HRH4KDM1ACCNA2CDK2 | |
| SCHEMBL18436682 | 0.80 | RAD52 (0.38) | HRH4ACP1KDM4AKDM5BKDM1A | |
| SCHEMBL18436897 | 0.79 | KDM4A (0.36) | HRH4KDM4AKDM5BCYP11B1CYP11B2 | |
| SCHEMBL18436757 | 0.78 | HRH4 (0.43) | HRH4KDM4AKDM5BKDM1ALAP3 | |
| SCHEMBL17128231 | 0.74 | BRS3 (0.45) | HRH4KDM4AKDM5BLAP3CYP11B1 | |
| SCHEMBL18436776 | 0.72 | HRH4 (0.35) | HRH4CYP11B1CYP11B2CCNA2CDK2 | |
| SCHEMBL17128081 | 0.72 | HRH4 (0.43) | HRH4KDM1AMAOBMAPT | |
| SCHEMBL21336962 | 0.71 | HRH4 (0.40) | HRH4KDM4AKDM5BKDM1ACYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3124482-A1 | QUINOLINE DERIVATIVES AS SMO INHIBITORS | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2017-02-01 | — | — | EP | disclosed |