Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18436994 | 0.81 | L3MBTL1 (0.41) | HRH3KMT2AALDH1A1RAB9AGAA | |
| SCHEMBL18436330 | 0.81 | L3MBTL1 (0.41) | HRH3KMT2AALDH1A1RAB9AGAA | |
| SCHEMBL14144924 | 0.80 | KMT2A (0.47) | HRH3KMT2AALDH1A1RAB9AGAA | |
| SCHEMBL1934299 | 0.80 | ALDH1A1 (0.40) | HRH3KMT2AALDH1A1RAB9AGAA | |
| SCHEMBL1934298 | 0.80 | ALDH1A1 (0.40) | HRH3KMT2AALDH1A1RAB9AGAA | |
| SCHEMBL19012765 | 0.78 | OGA (0.41) | HRH3KMT2AALDH1A1RAB9AGAA | |
| SCHEMBL19001122 | 0.78 | LMNA (0.59) | HRH3KMT2AALDH1A1RAB9AGAA | |
| SCHEMBL21336753 | 0.78 | HRH3 (0.36) | HRH3KMT2AALDH1A1RAB9AGAA | |
| SCHEMBL19001040 | 0.78 | LMNA (0.59) | HRH3KMT2AALDH1A1RAB9AGAA | |
| SCHEMBL19012345 | 0.78 | OGA (0.43) | HRH3KMT2AALDH1A1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3124482-A1 | QUINOLINE DERIVATIVES AS SMO INHIBITORS | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2017-02-01 | — | — | EP | disclosed |