SCHEMBL184380

SCHEMBL184380

O=Cc1cccc(Oc2ccc(F)cc2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 0.62
MAOB P27338 7/20 0.62
MAPT P10636 4/20 0.50
ALDH1A1 P00352 4/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
LMNA P02545 2/20 0.50
TP53 P04637 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
ALOX12 P18054 1/20 0.50
NFKB1 P19838 1/20 0.50
MAPK1 P28482 1/20 0.50
CYP2C19 P33261 1/20 0.50
HIF1A Q16665 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30584498 1.00 MAOA (0.62) MAOAMAOBMAPTALDH1A1MEN1
Ammonia Solution, Strong SCHEMBL6557053 0.98 MAOA (0.60) MAOAMAOBMAPTALDH1A1MEN1
SCHEMBL6856729 0.91 SRC (0.56) MAOAMAOBMAPTALDH1A1MEN1
SCHEMBL6557043 0.88 MAOA (0.51) MAOAMAOBMAPTALDH1A1MEN1
SCHEMBL2534036 0.87 MAOA (0.62) MAOAMAOBMAPTALDH1A1MEN1
SCHEMBL11222905 0.87 MAOB (0.59) MAOAMAOBMAPTALDH1A1MEN1
SCHEMBL6853633 0.87 SRC (0.53) MAOAMAOBMAPTALDH1A1MEN1
SCHEMBL31599170 0.87 SRC (0.53) MAOAMAOBMAPTALDH1A1MEN1
SCHEMBL6849018 0.87 SRC (0.60) MAOAMAOBMAPTALDH1A1MEN1
SCHEMBL30631693 0.87 SRC (0.60) MAOAMAOBMAPTALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118439937-A Synthetic method of 4-fluoro-3-phenoxybenzaldehyde serving as key intermediate of insect repellent 康龙化成(绍兴)药业有限公司 2024-08-06 CN claimed
CN-116410070-A Production process of p-fluoro-m-phenoxy benzaldehyde 江苏优嘉植物保护有限公司 2023-07-11 CN claimed
WO-1999038833-A1 PROCESS FOR THE HALOGENATION OF ALDEHYDES AND KETONES BROMINE COMPOUNDS LTD. (IL) 1999-08-05 WO claimed
US-20260062443-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMA INC (US) 2026-03-05 US disclosed
CN-223875002-U Byproduct collection and storage mechanism for preparing p-fluoro-m-phenoxy benzaldehyde 湖南道仕医药科技有限公司 2026-02-06 CN disclosed
CN-223875002-U Byproduct collection and storage mechanism for preparing p-fluoro-m-phenoxy benzaldehyde 湖南道仕医药科技有限公司 2026-02-06 CN disclosed
EP-4273143-B1 DERIVATIVE OF 2,5-DIKETOPIPERAZINE COMPOUND, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF DALIAN WZ PROBIOTICS AD HEALTH CO LTD (CN) 2025-05-21 EP disclosed
EP-3936192-B1 PYRROLOPYRAZOLE DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2025-04-09 EP disclosed
US-12240855-B2 Pyrrolopyrazole derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2025-03-04 US disclosed
CN-118439937-A Synthetic method of 4-fluoro-3-phenoxybenzaldehyde serving as key intermediate of insect repellent 康龙化成(绍兴)药业有限公司 2024-08-06 CN disclosed
US-20240140941-A1 DERIVATIVE OF 2,5-DIKETOPIPERAZINE COMPOUND, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF DALIAN WZ PROBIOTICS AD HEALTH CO., LTD (CN) 2024-05-02 US disclosed
US-4309555-A Novel cyclopropane derivatives CIBA-GEIGY CORPORATION (US) 1982-01-05 US disclosed
EP-0041021-A2 Cyclopropane carboxylic acid derivatives, their preparation, their use against parasites in plants and animals, their compositions and their intermediates ROUSSEL-UCLAF (FR) 1981-12-02 EP disclosed
US-4293504-A Process for preparing optically active α-cyano-3-(4-halogenophenoxy)-benzyl 2-(4-chlorophenyl)isovalerate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-10-06 US disclosed
US-4279923-A Combating pests with 3-(2,3-dichloro-3,3-difluoro-prop-1-en-1-yl)-2,2-dimethyl-cyclo-propanecarboxylic acid fluoro-benzyl esters BAYER AKTIENGESELLSCHAFT (DE) 1981-07-21 US disclosed
EP-0029543-A1 Fluorinated benzylic esters of spirocarboxylic acids, process for their preparation and their use in pesticides BAYER AG (DE) 1981-06-03 EP disclosed
EP-0029515-A1 Fluoro-substituted 2,2,3,3-tetramethylcyclopropane-1-carboxylic acid benzyl esters, process for their preparation and their use in pesticides BAYER AG (DE) 1981-06-03 EP disclosed
EP-0026437-A1 3-(2,3-dichloro-3,3-difluoro-prop-1-en-1-yl)2,2 dimethyl cyclopropionic acid fluorobenzyl esters, process for their manufacture and their use in pesticides BAYER AG (DE) 1981-04-08 EP disclosed
EP-0025925-A1 Process for the preparation of alpha-cyano-phenoxy benzylic esters BAYER AG (DE) 1981-04-01 EP disclosed
US-4242357-A INSECTICIDES, MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 1980-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062443-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS C9, SSB, C1S MAOA 3388/4885MAOB 2275/4885MAPT 1355/4885
US-20240140941-A1 DERIVATIVE OF 2,5-DIKETOPIPERAZINE COMPOUND, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF WEE1, WEE2, CYP51A1 MAOA 3832/4885MAOB 3540/4885MAPT 173/4885
US-12240855-B2 Pyrrolopyrazole derivative PTDSS1, PTDSS2, SMPD1 MAOA 4824/4885MAOB 4731/4885MAPT 4781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.