Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT1 | P04628 | 9/20 | 0.73 |
| ▸ | TGFBR1 | P36897 | 8/20 | 0.73 |
| ▸ | CLK2 | P49760 | 11/20 | 0.73 |
| ▸ | CLK3 | P49761 | 11/20 | 0.73 |
| ▸ | DYRK1A | Q13627 | 11/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18480578 | 0.94 | WNT1 (0.81) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL18476091 | 0.94 | CLK2 (0.74) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL18480517 | 0.94 | WNT1 (0.64) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL21283933 | 0.91 | CLK2 (0.77) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL18454226 | 0.91 | CLK2 (0.74) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL20454102 | 0.91 | CLK2 (0.88) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL17566145 | 0.90 | WNT1 (0.90) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL18480956 | 0.90 | WNT1 (0.83) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL18445155 | 0.89 | CLK2 (0.77) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL18438369 | 0.89 | CLK2 (0.63) | WNT1TGFBR1CLK2CLK3DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10392383-B2 | 3-(1H-benzo[d]imidazol-2-yl)-1H-pyrazolo[4,3-b]pyridines and therapeutic uses thereof | SAMUMED, LLC (US) | 2019-08-27 | — | — | US | claimed |
| WO-2017023989-A1 | 3-(1H-BENZO[D]IMIDAZOL-2-YL)-1H-PYRAZOLO[4,3-B]PYRIDINES AND THERAPEUTIC USES THEREOF | SAMUMED, LLC. (US) | 2017-02-09 | — | — | WO | claimed |
| US-10392383-B2 | 3-(1H-benzo[d]imidazol-2-yl)-1H-pyrazolo[4,3-b]pyridines and therapeutic uses thereof | SAMUMED, LLC (US) | 2019-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392383-B2 | 3-(1H-benzo[d]imidazol-2-yl)-1H-pyrazolo[4,3-b]pyridines and therapeutic uses thereof | WNT1, WNT3, WNT3A | WNT1 1/4885TGFBR1 503/4885CLK2 2158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.