Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18475393 | 0.85 | CTSD (0.51) | HSD17B10KMT2APOLBTSHRRECQL | |
| SCHEMBL18475431 | 0.85 | CTSD (0.51) | HSD17B10KMT2APOLBTSHRRECQL | |
| SCHEMBL25920599 | 0.82 | TSHR (0.52) | SMN1; SMN2HSD17B10KMT2APOLBTSHR | |
| SCHEMBL17839975 | 0.81 | HSD17B10 (0.49) | HSD17B10KMT2APOLBTSHRHPGD | |
| SCHEMBL29453458 | 0.81 | HSD17B10 (0.49) | HSD17B10KMT2APOLBTSHRHPGD | |
| SCHEMBL21543849 | 0.81 | SMN1; SMN2 (0.51) | CYP1A2CYP2C19SMN1; SMN2HSD17B10KMT2A | |
| SCHEMBL18493737 | 0.80 | HSD17B10 (0.48) | SMN1; SMN2HSD17B10KMT2APOLBTSHR | |
| SCHEMBL24172945 | 0.80 | PTPN1 (0.46) | HSD17B10KMT2APOLBTDP1MEN1 | |
| SCHEMBL17839574 | 0.79 | PTPN1 (0.45) | HSD17B10KMT2APOLBTDP1 | |
| SCHEMBL29453449 | 0.79 | PTPN1 (0.45) | HSD17B10KMT2APOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331906-A1 | TUNABLE ENDOGENOUS PROTEIN DEGRADATION | Dana-Farber Cancer Institute, Inc. (US) | 2018-06-13 | — | — | EP | disclosed |
| WO-2017024319-A1 | TUNABLE ENDOGENOUS PROTEIN DEGRADATION | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-02-09 | — | — | WO | disclosed |