Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29453453 | 0.87 | PTPN1 (0.43) | TSHRRECQLALDH1A1NPSR1HSD17B10 | |
| SCHEMBL17839751 | 0.87 | PTPN1 (0.43) | TSHRRECQLALDH1A1NPSR1HSD17B10 | |
| SCHEMBL18475393 | 0.86 | CTSD (0.51) | TSHRRECQLALDH1A1HSD17B10KMT2A | |
| SCHEMBL18475431 | 0.86 | CTSD (0.51) | TSHRRECQLALDH1A1HSD17B10KMT2A | |
| SCHEMBL24391150 | 0.85 | PTPN1 (0.42) | TSHRRECQLALDH1A1HSD17B10HPGD | |
| SCHEMBL18445963 | 0.82 | CYP1A2 (0.49) | TSHRRECQLALDH1A1HSD17B10KMT2A | |
| SCHEMBL18493737 | 0.81 | HSD17B10 (0.48) | TSHRALDH1A1NPSR1HSD17B10KMT2A | |
| SCHEMBL24172945 | 0.78 | PTPN1 (0.46) | NPSR1HSD17B10KMT2APOLBMEN1 | |
| SCHEMBL21543887 | 0.78 | ALDH1A1 (0.46) | ALDH1A1NPSR1HSD17B10KMT2AHPGD | |
| SCHEMBL17839574 | 0.77 | PTPN1 (0.45) | HSD17B10KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256470-B1 | METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL MOLECULES | DANA FARBER CANCER INST INC (US) | 2023-07-26 | — | — | EP | disclosed |