Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | JAK2 | O60674 | 2/20 | 0.50 |
| ▸ | JAK3 | P52333 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.47 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.47 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.47 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.47 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.47 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.47 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.47 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17560899 | 0.84 | ATP1A1 (0.49) | FFAR2JAK2JAK3KMT2AHPGD | |
| SCHEMBL4312347 | 0.83 | MAPKAPK2 (0.56) | KDM4EJAK2JAK3ALDH1A1KMT2A | |
| SCHEMBL2054165 | 0.83 | MAPKAPK2 (0.56) | KDM4EJAK2JAK3ALDH1A1KMT2A | |
| SCHEMBL23780413 | 0.80 | ALDH1A1 (0.54) | KDM4EJAK2JAK3ALDH1A1HPGD | |
| SCHEMBL23291896 | 0.80 | ALDH1A1 (0.54) | KDM4EJAK2JAK3ALDH1A1HPGD | |
| SCHEMBL23291971 | 0.77 | HDAC3 (0.41) | FFAR2KDM4EJAK2JAK3ALDH1A1 | |
| SCHEMBL23780410 | 0.77 | HDAC3 (0.41) | FFAR2KDM4EJAK2JAK3ALDH1A1 | |
| SCHEMBL1367151 | 0.77 | JAK2 (0.68) | JAK2JAK3JAK1TYK2GPR55 | |
| SCHEMBL14954526 | 0.77 | JAK2 (0.57) | FFAR2JAK2JAK3JAK1TYK2 | |
| SCHEMBL30765607 | 0.75 | GPR55 (0.51) | JAK2JAK3KMT2AHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331863-A1 | NOVEL COMPOUNDS AS ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2018-06-13 | — | — | EP | disclosed |
| WO-2017021879-A1 | NOVEL COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2017-02-09 | — | — | WO | disclosed |