Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Glutamic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 2/20 | 0.86 |
| ▸ | GRM6 | O15303 | 2/20 | 0.86 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.86 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.86 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.86 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.86 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.86 |
| ▸ | GSR | P00390 | 1/20 | 0.86 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.86 |
| ▸ | GRM5 | P41594 | 1/20 | 0.86 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.86 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.86 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.86 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.86 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.86 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.86 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.86 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.86 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.86 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Glutamate SCHEMBL15797537 | 1.00 | GRM8 (0.86) | GRM8GRM6GRM7GRM4CYP1A2 | |
| D-Glutamate SCHEMBL28509459 | 1.00 | GRM8 (0.86) | GRM8GRM6GRM7GRM4CYP1A2 | |
| D-Glutamate SCHEMBL27884184 | 1.00 | GRM8 (0.86) | GRM8GRM6GRM7GRM4CYP1A2 | |
| D-Glutamate SCHEMBL28330083 | 1.00 | GRM8 (0.86) | GRM8GRM6GRM7GRM4CYP1A2 | |
| D-Glutamate SCHEMBL184512 | 1.00 | GRM8 (0.86) | GRM8GRM6GRM7GRM4CYP1A2 | |
| Glutamic Acid SCHEMBL2803034 | 1.00 | GRM8 (0.86) | GRM8GRM6GRM7GRM4CYP1A2 | |
| D-Glutamate SCHEMBL787885 | 0.98 | GRM8 (0.82) | GRM8GRM6GRM7GRM4CYP1A2 | |
| D-Glutamate SCHEMBL787628 | 0.98 | GRM8 (0.82) | GRM8GRM6GRM7GRM4CYP1A2 | |
| D-Glutamate SCHEMBL20528822 | 0.98 | GRM8 (0.82) | GRM8GRM6GRM7GRM4CYP1A2 | |
| Glutamic Acid SCHEMBL381869 | 0.98 | GRM8 (0.82) | GRM8GRM6GRM7GRM4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3275 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122080389-A | Esterified polymer and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-117822132-B | Biological enzyme pile-steaming degumming method for ramie | 江南大学 | 2026-05-15 | — | — | CN | claimed |
| US-12570585-B2 | Methods and compositions for use in agricultural processes | SOLUGEN, INC. (US) | 2026-03-10 | — | — | US | claimed |
| WO-2026042045-A1 | INDOLICIDINE-CONTAINING COMPOSITIONS FOR PERSONAL CARE/HYGIENE APPLICATIONS | ITC LIMITED (IN) | 2026-02-26 | — | — | WO | claimed |
| US-20260008028-A1 | Super Absorbent Polymer Composition and Preparation Method Thereof | LG CHEM, LTD. (KR) | 2026-01-08 | — | — | US | claimed |
| EP-3529343-B1 | AMBIENT MOISTURE-ACTIVATED SURFACE TREATMENT POWDER | Sterilex LLC (US) | 2025-12-17 | — | — | EP | claimed |
| EP-4660233-A1 | COMPOSITION OF SUPER ABSORBENT POLYMER AND PREPARATION METHOD THEREOF | LG CHEM, LTD. (KR) | 2025-12-10 | — | — | EP | claimed |
| WO-2025226916-A1 | PARTICULATE LAUNDRY SCENT ADDITIVE INCLUDING A BUILDER | THE PROCTER & GAMBLE COMPANY (US) | 2025-10-30 | — | — | WO | claimed |
| US-20250333667-A1 | PARTICULATE LAUNDRY SCENT ADDITIVE INCLUDING A BUILDER | PROCTER & GAMBLE (US) | 2025-10-30 | — | — | US | claimed |
| EP-4638681-A1 | PROCESS FOR PROVIDING A COMPOSITION COMPRISING AT LEAST ONE AMINOCARBOXYLATE COMPLEXING AGENT | BASF SE (DE) | 2025-10-29 | — | — | EP | claimed |
| WO-2010045686-A1 | CLEANING METHOD | ORICA AUSTRALIA PTY LTD (AU) | 2010-04-29 | — | — | WO | claimed |
| EP-2170808-A2 | CHELATING AGENT BASED IONIC LIQUIDS, A PROCESS TO PREPARE THEM, AND THEIR USE | Akzo Nobel N.V. (NL) | 2010-04-07 | — | — | EP | claimed |
| WO-2009048345-A1 | MOLLUSCICIDE | ZUPH 'BEST PET' (PL) | 2009-04-16 | — | — | WO | claimed |
| WO-2009016235-A2 | CHELATING AGENT BASED IONIC LIQUIDS, A PROCESS TO PREPARE THEM, AND THEIR USE | AKZO NOBEL N.V. (NL) | 2009-02-05 | — | — | WO | claimed |
| US-20080300159-A1 | Mixed Powder or Mixed Granule Based on Glutamic Acid-N, N-Diacetic Acid and Salts Thereof | BASF SE (DE) | 2008-12-04 | — | — | US | claimed |
| WO-2008137517-A1 | SYSTEMS, COMPOSITIONS, AND/OR METHODS FOR DEPOLYMERIZING CELLULOSE AND/OR STARCH | HYDRITE CHEMICAL CO. (US) | 2008-11-13 | — | — | WO | claimed |
| US-6703451-B2 | Superabsorbent resin composition | KAO CORPORATION (JP) | 2004-03-09 | — | — | US | claimed |
| EP-0889063-B1 | Superabsorbent resin composition | KAO CORP (JP) | 2003-09-10 | — | — | EP | claimed |
| US-20010053826-A1 | Superabsorbent resin composition | KAO CORPORATION | 2001-12-20 | — | — | US | claimed |
| EP-0889063-A1 | Superabsorbent resin composition | KAO CORPORATION (JP) | 1999-01-07 | — | — | EP | claimed |