Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Glutamic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 2/20 | 0.82 |
| ▸ | GRM6 | O15303 | 2/20 | 0.82 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.82 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.82 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.82 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.82 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.82 |
| ▸ | GSR | P00390 | 1/20 | 0.82 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.82 |
| ▸ | GRM5 | P41594 | 1/20 | 0.82 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.82 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.82 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.82 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.82 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.82 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.82 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.82 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.82 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.82 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Glutamate SCHEMBL28725412 | 1.00 | GRM8 (0.82) | GRM8GRM6GRM7GRM4CYP1A2 | |
| D-Glutamate SCHEMBL787628 | 1.00 | GRM8 (0.82) | GRM8GRM6GRM7GRM4CYP1A2 | |
| D-Glutamate SCHEMBL787900 | 1.00 | GRM8 (0.82) | GRM8GRM6GRM7GRM4CYP1A2 | |
| D-Glutamate SCHEMBL20528822 | 1.00 | GRM8 (0.82) | GRM8GRM6GRM7GRM4CYP1A2 | |
| Glutamic Acid SCHEMBL184513 | 0.98 | GRM8 (0.86) | GRM8GRM6GRM7GRM4CYP1A2 | |
| Glutamic Acid SCHEMBL2803034 | 0.98 | GRM8 (0.86) | GRM8GRM6GRM7GRM4CYP1A2 | |
| D-Glutamate SCHEMBL15797537 | 0.98 | GRM8 (0.86) | GRM8GRM6GRM7GRM4CYP1A2 | |
| D-Glutamate SCHEMBL184512 | 0.98 | GRM8 (0.86) | GRM8GRM6GRM7GRM4CYP1A2 | |
| D-Glutamate SCHEMBL28509459 | 0.98 | GRM8 (0.86) | GRM8GRM6GRM7GRM4CYP1A2 | |
| D-Glutamate SCHEMBL28330083 | 0.98 | GRM8 (0.86) | GRM8GRM6GRM7GRM4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230116039-A1 | DISINFECTION SOLUTION WITH TWO-PART FORMULATION | ASP GLOBAL MFG GMBH (CH) | 2023-04-13 | — | — | US | claimed |
| CN-113786353-B | Cream containing DNA sodium anti-aging combined factor and preparation method thereof | 广州欧正化妆品技术研究院有限公司 | 2023-03-14 | — | — | CN | claimed |
| EP-4138560-A1 | DISINFECTION SOLUTION WITH TWO-PART FORMULATION | ASP Global Manufacturing GmbH (CH) | 2023-03-01 | — | — | EP | claimed |
| CN-115382305-A | Method and device for fully automatically cleaning multiple security filter elements of power plant | 华能荆门热电有限责任公司 | 2022-11-25 | — | — | CN | claimed |
| CN-113149940-B | Purification process of maleic anhydride heavy component | 宁波浙铁江宁化工有限公司 | 2022-09-30 | — | — | CN | claimed |
| CN-115109665-A | Safe and environment-friendly disinfection and sterilization laundry detergent and preparation method thereof | 成都汉德尔新材料有限公司 | 2022-09-27 | — | — | CN | claimed |
| CN-114908341-B | Special surface treating agent for PCB chemical nickel-palladium-gold plating layer and preparation method thereof | 深圳市板明科技股份有限公司 | 2022-09-27 | — | — | CN | claimed |
| CN-114908341-A | Special surface treating agent for PCB chemical nickel-palladium-gold plating layer and preparation method thereof | 深圳市板明科技股份有限公司 | 2022-08-16 | — | — | CN | claimed |
| CN-111335864-B | High-permeability heterogeneous sandstone reservoir steering acidification method | 西南石油大学 | 2022-07-29 | — | — | CN | claimed |
| CN-114751529-A | Environment-friendly phosphorus-free chelating agent and preparation method thereof | 宜城成雄织造有限公司 | 2022-07-15 | — | — | CN | claimed |
| CN-111066437-A | Soil conditioning fluid for reducing chloride ion content in tobacco leaves and application method thereof | 中国烟草总公司郑州烟草研究院 | 2020-04-28 | — | — | CN | claimed |
| CN-110819467-A | Detergent without harmful substances or skin irritative substances | 荆州市活力二八家化有限公司 | 2020-02-21 | — | — | CN | claimed |
| CN-110777019-A | Fabric detergent containing dodecyl diethylenetriamine and having mite killing function | 荆州市活力二八家化有限公司 | 2020-02-11 | — | — | CN | claimed |
| CN-110724608-A | Neutral concentrated laundry detergent and preparation method thereof | 威莱(广州)日用品有限公司 | 2020-01-24 | — | — | CN | claimed |
| CN-109135954-A | A kind of environment-friendly high-efficiency liquid detergent | 北京洛娃日化有限公司 | 2019-01-04 | — | — | CN | claimed |
| CN-108192771-A | A kind of two chamber multienzyme of surgical instrument coagulates pearl and preparation method thereof | 南京巨鲨显示科技有限公司 | 2018-06-22 | — | — | CN | claimed |
| US-9027647-B2 | Treatment fluids containing a biodegradable chelating agent and methods for use thereof | HALLIBURTON ENERGY SERVICES, INC. (US) | 2015-05-12 | — | — | US | claimed |
| EP-2686399-A1 | TREATMENT FLUIDS CONTAINING A BIODEGRADABLE CHELATING AGENT AND METHODS FOR USE THEREOF | Halliburton Energy Services, Inc. (US) | 2014-01-22 | — | — | EP | claimed |
| WO-2012127183-A1 | TREATMENT FLUIDS CONTAINING A BIODEGRADABLE CHELATING AGENT AND METHODS FOR USE THEREOF | HALIBURTON ENERGY SERVICES, INC. (GB) | 2012-09-27 | — | — | WO | claimed |
| US-20120067576-A1 | TREATMENT FLUIDS CONTAINING A BIODEGRADABLE CHELATING AGENT AND METHODS FOR USE THEREOF | HALLIBURTON ENERGY SERVICES, INC. (US) | 2012-03-22 | — | — | US | claimed |