Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1843618 | 0.84 | MPO (0.46) | ACHESLC6A4MPO | |
| Hydrochloric Acid SCHEMBL459039 | 0.82 | MPO (0.45) | SLC6A4MPO | |
| Hydrochloric Acid SCHEMBL8679453 | 0.77 | MPO (0.52) | DRD2MPO | |
| SCHEMBL8788480 | 0.76 | ACHE (0.45) | ACHEDRD2SLC6A4 | |
| SCHEMBL8786866 | 0.76 | ACHE (0.50) | ACHEDRD2SLC6A4 | |
| SCHEMBL8506902 | 0.76 | ACHE (0.50) | ACHEDRD2SLC6A4 | |
| SCHEMBL8788398 | 0.75 | ACHE (0.44) | ACHEDRD2SLC6A4 | |
| SCHEMBL8787897 | 0.74 | ACHE (0.48) | ACHEDRD2SLC6A4 | |
| SCHEMBL8787796 | 0.74 | ACHE (0.48) | ACHEDRD2SLC6A4 | |
| SCHEMBL8787733 | 0.73 | DRD2 (0.44) | ACHEDRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321311-A1 | SYNTHESIS OF PALIPERIDONE | Synthon B.V. (NL) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010003702-A9 | SYNTHESIS OF PALIPERIDONE | SYNTHON B.V. (NL) | 2010-12-02 | — | — | WO | disclosed |
| EP-2235009-A1 | SYNTHESIS OF PALIPERIDONE | Synthon B.V. (NL) | 2010-10-06 | — | — | EP | disclosed |
| WO-2010003702-A1 | SYNTHESIS OF PALIPERIDONE | SYNTHON B.V. (NL) | 2010-01-14 | — | — | WO | disclosed |
| WO-2009074333-A1 | SYNTHESIS OF PALIPERIDONE | SYNTHON B.V. (NL) | 2009-06-18 | — | — | WO | disclosed |