Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | XBP1 | P17861 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18456030 | 0.91 | ADORA2A (0.36) | ATMMEN1KMT2AADORA2ACYP1A2 | |
| SCHEMBL18455710 | 0.90 | ATM (0.50) | ATMMEN1KMT2AADORA2ANPC1 | |
| SCHEMBL18456034 | 0.90 | MEN1 (0.46) | ATMMEN1KMT2AADORA2ANPC1 | |
| SCHEMBL18456151 | 0.89 | WHR1 (0.36) | ATMMEN1KMT2ANPC1HTT | |
| SCHEMBL18455709 | 0.89 | MEN1 (0.52) | ATMMEN1KMT2AADORA2ANPC1 | |
| SCHEMBL18456318 | 0.88 | MEN1 (0.47) | ATMMEN1KMT2AADORA2AMAPT | |
| SCHEMBL18456316 | 0.84 | ADORA2A (0.35) | ATMMEN1KMT2AADORA2ACYP1A2 | |
| SCHEMBL18456219 | 0.83 | MEN1 (0.36) | ATMMEN1KMT2AADORA2ANPC1 | |
| SCHEMBL18456216 | 0.83 | ADORA2A (0.38) | ATMMEN1KMT2AADORA2ACYP1A2 | |
| SCHEMBL18456161 | 0.83 | MEN1 (0.46) | ATMMEN1KMT2ANPC1XBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11201296-B2 | Compounds having fluorene structures | MERCK PATENT GMBH (DE) | 2021-12-14 | — | — | US | disclosed |
| EP-3328850-B1 | COMPOUNDS HAVING FLUORENE STRUCTURES | MERCK PATENT GMBH (DE) | 2020-11-11 | — | — | EP | disclosed |
| US-20180226587-A1 | COMPOUNDS HAVING FLUORENE STRUCTURES | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| US-20180226587-A1 | COMPOUNDS HAVING FLUORENE STRUCTURES | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| WO-2017016667-A1 | COMPOUNDS HAVING FLUORENE STRUCTURES | MERCK PATENT GMBH (DE) | 2017-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180226587-A1 | COMPOUNDS HAVING FLUORENE STRUCTURES | FSCN1, EFNA1, FLNA | ATM 4239/4885MEN1 1658/4885KMT2A 2095/4885 |
| US-11201296-B2 | Compounds having fluorene structures | FSCN1, EFNA1, FLNA | ATM 4239/4885MEN1 1658/4885KMT2A 2095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.