Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 2/20 | 0.47 |
| ▸ | BTK | Q06187 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18456585 | 0.82 | TP53 (0.68) | TP53MAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL20462812 | 0.81 | TP53 (0.72) | TP53MAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL18456587 | 0.79 | TP53 (0.69) | TP53MAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL18456581 | 0.72 | LMNA (0.66) | TP53MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL1294980 | 0.72 | ALDH1A1 (0.71) | TP53MAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL20462652 | 0.70 | LMNA (0.69) | TP53MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL18456663 | 0.70 | LMNA (0.61) | TP53MAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL31428602 | 0.70 | ALDH1A1 (1.00) | TP53MAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL5692309 | 0.70 | ALDH1A1 (1.00) | TP53MAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL18456601 | 0.69 | LMNA (0.72) | TP53MAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017019772-A1 | MODULATORS OF MYOCYTE LIPID ACCUMULATION AND INSULIN RESISTANCE AND METHODS OF USE THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2017-02-02 | — | — | WO | disclosed |