Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.80 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MITF | O75030 | 1/20 | 0.59 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.59 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5692309 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL5692416 | 0.87 | ALDH1A1 (0.77) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL1294980 | 0.83 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL30163498 | 0.81 | ALDH1A1 (0.69) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL25207556 | 0.81 | ALDH1A1 (0.68) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL8220477 | 0.81 | KDM4E (0.70) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL8220489 | 0.81 | KDM4E (0.70) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL8220485 | 0.81 | KDM4E (0.70) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL18456601 | 0.80 | LMNA (0.72) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL5064247 | 0.79 | KDM4E (0.69) | ALDH1A1KDM4EHPGDGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | ALDH1A1 2352/4885KDM4E 2663/4885HPGD 4233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.