SCHEMBL18458570

SCHEMBL18458570

NCC1CCC(c2cc(F)c(-c3cc(F)c(F)c(F)c3)c(F)c2)CC1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ HRH4 Q9H3N8 2/20 0.32
▸ HTR2A P28223 1/20 0.30
▸ HTR2C P28335 1/20 0.30
▸ HTR2B P41595 1/20 0.30
▸ BPTF Q12830 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18458839 0.90 HTR2C (0.35) HRH4HTR2AHTR2CHTR2BBPTF
SCHEMBL18458610 0.85 HTR2A (0.33) HRH4HTR2AHTR2CHTR2BBPTF
SCHEMBL18458568 0.85 HTR2C (0.41) HRH4HTR2AHTR2CHTR2BBPTF
SCHEMBL15965525 0.84 ALDH1A1 (0.33) —
SCHEMBL18083580 0.84 ALDH1A1 (0.33) —
SCHEMBL8021856 0.82 IDO1 (0.30) —
SCHEMBL15965526 0.82 CYP2C9 (0.40) —
SCHEMBL8021854 0.82 IDO1 (0.30) —
SCHEMBL18800297 0.81 HTR2A (0.38) HTR2AHTR2CHTR2BBPTF
SCHEMBL18458621 0.81 DGAT1 (0.37) HTR2AHTR2CHTR2BBPTF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11326103-B2 Liquid crystal display device DIC CORPORATION (JP) 2022-05-10 — — US disclosed
US-20200354633-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2020-11-12 — — US disclosed
US-10414979-B2 Composition and liquid crystal display device using the same DIC CORPORATION (JP) 2019-09-17 — — US disclosed
US-10400168-B2 Composition and liquid crystal display device using the same DIC CORPORATION (JP) 2019-09-03 — — US disclosed
US-10344211-B2 Liquid crystal composition and liquid crystal display element using same DIC CORPORATION (JP) 2019-07-09 — — US disclosed
US-20190119575-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2019-04-25 — — US disclosed
US-10208250-B2 Liquid crystal composition and liquid crystal display element using same DIC CORPORATION (JP) 2019-02-19 — — US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 — — US disclosed
US-20170355906-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-12-14 — — US disclosed
US-9828549-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-11-28 — — US disclosed
US-9822304-B2 Liquid crystal composition and liquid crystal display element containing the same DIC CORPORATION (JP) 2017-11-21 — — US disclosed
US-20170327742-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2017-11-16 — — US disclosed
US-20170306231-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2017-10-26 — — US disclosed
US-20170226420-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2017-08-10 — — US disclosed
US-20170210986-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2017-07-27 — — US disclosed
US-9688913-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-06-27 — — US disclosed
US-9650572-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-05-16 — — US disclosed
US-9637684-B2 Composition and liquid crystal display element using same DIC CORPORATION (JP) 2017-05-02 — — US disclosed
US-9580654-B2 Liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2017-02-28 — — US disclosed
US-20170029700-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2017-02-02 — — US disclosed
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