SCHEMBL1845901

SCHEMBL1845901

CC(=O)Oc1c(C)occc1=O

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.55
LMNA P02545 4/20 0.52
KMT2A Q03164 2/20 0.52
MAPT P10636 2/20 0.52
MEN1 O00255 1/20 0.52
HTT P42858 1/20 0.52
ATM Q13315 1/20 0.52
KDM4E B2RXH2 3/20 0.50
GAA P10253 1/20 0.49
HSD17B10 Q99714 2/20 0.44
POLB P06746 1/20 0.44
LDHA P00338 8/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 1/20 0.39
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17070856 0.83 SMN1; SMN2 (0.50) SMN1; SMN2LMNAKMT2AMAPTMEN1
SCHEMBL11548502 0.82 SMN1; SMN2 (0.49) SMN1; SMN2LMNAKMT2AMAPTMEN1
SCHEMBL31113422 0.81 HSD17B10 (0.54) SMN1; SMN2LMNAKMT2AMAPTMEN1
SCHEMBL1193595 0.81 HSD17B10 (0.54) SMN1; SMN2LMNAKMT2AMAPTMEN1
SCHEMBL14764002 0.81 SMN1; SMN2 (0.51) SMN1; SMN2LMNAKMT2AMAPTMEN1
SCHEMBL1044794 0.81 SMN1; SMN2 (0.51) SMN1; SMN2LMNAKMT2AMAPTMEN1
SCHEMBL1532533 0.81 SMN1; SMN2 (0.51) SMN1; SMN2LMNAKMT2AMAPTMEN1
SCHEMBL25334262 0.80 SMN1; SMN2 (0.50) SMN1; SMN2LMNAKMT2AMAPTMEN1
SCHEMBL10464105 0.80 SMN1; SMN2 (0.50) SMN1; SMN2LMNAKMT2AMAPTMEN1
SCHEMBL1843245 0.78 SMN1; SMN2 (0.49) SMN1; SMN2LMNAKMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250161182-A1 ANTIMICROBIAL COMPOSITIONS BIO-ACTIVES SYNERGIO LTD (IL) 2025-05-22 US claimed
CN-116574031-B Passion fruit aroma compound, preparation method thereof and passion fruit aroma essence 波顿香料股份有限公司 2024-12-06 CN claimed
EP-4469037-A1 ANTIMICROBIAL COMPOSITIONS Bio-Actives Synergio Ltd (IL) 2024-12-04 EP claimed
CN-116574031-A Passion fruit aroma compound, preparation method thereof and passion fruit aroma essence 波顿香料股份有限公司 2023-08-11 CN claimed
WO-2023144808-A1 ANTIMICROBIAL COMPOSITIONS BIO-ACTIVES SYNERGIO LTD (IL) 2023-08-03 WO claimed
CN-112553003-B Preparation method and application of fragrant raw material for showing sweet taste characteristics of Chinese-style cigarettes 河南中烟工业有限责任公司 2023-03-21 CN claimed
CN-110713476-B Synthesis method of 2, 3-dihydro-3, 5-dihydroxy-6-methyl-4H-pyran-4-one 河南中烟工业有限责任公司 2022-07-26 CN claimed
CN-110713476-A Synthesis method of 2, 3-dihydro-3, 5-dihydroxy-6-methyl-4H-pyran-4-one 河南中烟工业有限责任公司 2020-01-21 CN claimed
EP-2320745-A1 SWEETENER, METHODS OF PREPARING SWEETENER AND APPLICATIONS THEREOF Cargill, Incorporated (US) 2011-05-18 EP claimed
US-20110059218-A1 SWEETENER, METHODS OF PREPARING SWEETENER AND APPLICATIONS THEREOF CARGILL INCORPORATED (US) 2011-03-10 US claimed
WO-2009137838-A1 SWEETENER, METHODS OF PREPARING SWEETENER AND APPLICATIONS THEREOF CARGILL, INCORPORATED (US) 2009-11-12 WO claimed
US-20250161182-A1 ANTIMICROBIAL COMPOSITIONS BIO-ACTIVES SYNERGIO LTD (IL) 2025-05-22 US disclosed
CN-119584860-A Comprising biodegradable microcapsule composition 奇华顿股份有限公司 2025-03-07 CN disclosed
CN-116574031-B Passion fruit aroma compound, preparation method thereof and passion fruit aroma essence 波顿香料股份有限公司 2024-12-06 CN disclosed
EP-4469037-A1 ANTIMICROBIAL COMPOSITIONS Bio-Actives Synergio Ltd (IL) 2024-12-04 EP disclosed
CN-110713476-A Synthesis method of 2, 3-dihydro-3, 5-dihydroxy-6-methyl-4H-pyran-4-one 河南中烟工业有限责任公司 2020-01-21 CN disclosed
EP-2320745-A1 SWEETENER, METHODS OF PREPARING SWEETENER AND APPLICATIONS THEREOF Cargill, Incorporated (US) 2011-05-18 EP disclosed
US-20110059218-A1 SWEETENER, METHODS OF PREPARING SWEETENER AND APPLICATIONS THEREOF CARGILL INCORPORATED (US) 2011-03-10 US disclosed
WO-2009137838-A1 SWEETENER, METHODS OF PREPARING SWEETENER AND APPLICATIONS THEREOF CARGILL, INCORPORATED (US) 2009-11-12 WO disclosed
WO-2009092176-A2 METHOD OF FLAVORING GIVAUDAN SA (CH) 2009-07-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250161182-A1 ANTIMICROBIAL COMPOSITIONS NOD2, PYCARD, CLPP SMN1; SMN2 4274/4885LMNA 2204/4885KMT2A 4824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.