SCHEMBL18459062

SCHEMBL18459062

N#Cc1c(-c2ccccc2Cl)csc1Nc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.43
MAP2K1 Q02750 2/20 0.43
HTT P42858 1/20 0.43
RECQL P46063 1/20 0.43
ALDH1A1 P00352 4/20 0.40
GAA P10253 1/20 0.40
ADORA2A P29274 4/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
ADORA1 P30542 3/20 0.40
LMNA P02545 2/20 0.40
HPGD P15428 1/20 0.40
KMT2A Q03164 1/20 0.40
POLB P06746 2/20 0.39
STK10 O94804 2/20 0.38
SLK Q9H2G2 2/20 0.38
GSK3B P49841 1/20 0.38
KDM4E B2RXH2 2/20 0.37
MAPK1 P28482 1/20 0.37
CACNA1B Q00975 1/20 0.37
APBA1 Q02410 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18458656 0.83 ADORA1 (0.49) MAPTMAP2K1HTTRECQLALDH1A1
SCHEMBL18458828 0.82 MAPT (0.48) MAPTMAP2K1HTTRECQLALDH1A1
SCHEMBL18459063 0.82 ALOX5 (0.49) MAPTMAP2K1HTTRECQLALDH1A1
SCHEMBL10654269 0.71 ALDH1A1 (0.47) MAPTALDH1A1GAAADORA2AL3MBTL1
SCHEMBL10658430 0.70 ALDH1A1 (0.39) MAPTALDH1A1GAAADORA2AL3MBTL1
SCHEMBL10651545 0.69 HSP90AA1 (0.40) MAPTHTTALDH1A1GAAADORA2A
SCHEMBL18458657 0.67 MAPT (0.40) MAPTALDH1A1GAAADORA2AL3MBTL1
SCHEMBL18458436 0.65 MAPT (0.39) MAPTHTTRECQLGAAADORA2A
SCHEMBL18458659 0.65 ALDH1A1 (0.41) HTTRECQLALDH1A1L3MBTL1LMNA
Cyanamide SCHEMBL444164 0.62 DPP4 (0.52) MAPTALDH1A1ADORA2AL3MBTL1ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017018617-A1 NOVEL COMPOUND, PHOTOSENSITIVE RESIN COMPOSITION CONTAINING SAME, AND COLOR FILTER 삼성에스디아이 주식회사 2017-02-02 WO disclosed