Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10651866 | 0.83 | KDM4E (0.47) | ALDH1A1KDM4EKMT2AHPGDLMNA | |
| SCHEMBL10653117 | 0.78 | ABL1 (0.40) | PTGS2ADORA2AADORA1 | |
| SCHEMBL10653342 | 0.77 | ATM (0.51) | ALDH1A1KDM4EKMT2AHPGDLMNA | |
| SCHEMBL10653380 | 0.74 | GRIA2 (0.33) | ALDH1A1KDM4EKMT2AHPGDLMNA | |
| SCHEMBL10654269 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4EKMT2AHPGDLMNA | |
| SCHEMBL10658430 | 0.72 | ALDH1A1 (0.39) | ALDH1A1KDM4EKMT2AHPGDLMNA | |
| SCHEMBL10654899 | 0.71 | KDM4E (0.43) | ALDH1A1KDM4EKMT2AHPGDLMNA | |
| SCHEMBL10652386 | 0.69 | GRIA2 (0.42) | ALDH1A1KMT2APTGS2MEN1MAPT | |
| SCHEMBL18459062 | 0.69 | MAPT (0.43) | HSP90AA1HSP90AB1ALDH1A1KDM4EKMT2A | |
| SCHEMBL18458657 | 0.67 | MAPT (0.40) | ALDH1A1KDM4EKMT2AHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273602-A1 | 3-Cyano-4-arylthiophenes | ELI LILLY AND COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |