SCHEMBL18459150

SCHEMBL18459150

Cc1ccc(CCc2ccc(CCC3CCC(C)CC3)cc2)cc1F

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.45
SLC6A4 P31645 2/20 0.45
SLC6A3 Q01959 2/20 0.45
DAO P14920 1/20 0.42
MAOB P27338 4/20 0.36
LMNA P02545 1/20 0.36
GPR84 Q9NQS5 1/20 0.35
PTGS1 P23219 1/20 0.34
PTGS2 P35354 1/20 0.34
DRD2 P14416 1/20 0.34
DRD4 P21917 1/20 0.34
MAOA P21397 2/20 0.33
KCNH2 Q12809 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17548009 0.97 SLC6A2 (0.47) SLC6A2SLC6A4SLC6A3DAOMAOB
SCHEMBL17548020 0.93 SLC6A2 (0.44) SLC6A2SLC6A4SLC6A3DAOMAOB
SCHEMBL18503377 0.89 HRH3 (0.40) SLC6A2SLC6A4SLC6A3MAOBLMNA
SCHEMBL27049743 0.87 MAOB (0.37) SLC6A2SLC6A4SLC6A3MAOBGPR84
SCHEMBL9979951 0.84 SLC6A2 (0.42) SLC6A2SLC6A4SLC6A3DAOMAOB
SCHEMBL8153283 0.84 SLC6A2 (0.42) SLC6A2SLC6A4SLC6A3DAOMAOB
SCHEMBL20259458 0.82 SLC6A2 (0.46) SLC6A2SLC6A4SLC6A3DAOMAOB
SCHEMBL19011929 0.82 MAOB (0.36) SLC6A2SLC6A4SLC6A3MAOBGPR84
SCHEMBL17548039 0.82 ESR2 (0.44) SLC6A2SLC6A4SLC6A3DAOPTGS1
SCHEMBL19887761 0.81 LMNA (0.38) SLC6A2SLC6A4SLC6A3DAOLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3551723-B1 ADDITIVES FOR LIQUID CRYSTAL MIXTURES MERCK PATENT GMBH (DE) 2023-09-20 EP disclosed
WO-2022068499-A1 THIOPHENE-CONTAINING LIQUID CRYSTAL COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 北京八亿时空液晶科技股份有限公司 2022-04-07 WO disclosed
US-11053441-B2 Liquid crystal composition and liquid crystal display device JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-07-06 US disclosed
US-10759997-B2 Polymerizable compound, liquid crystal medium containing same and liquid crystal display device SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2020-09-01 US disclosed
US-20200123443-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2020-04-23 US disclosed
WO-2019233978-A1 ADDITIVES FOR LIQUID-CRYSTAL MIXTURES MERCK PATENT GMBH (DE) 2019-12-12 WO disclosed
EP-3037501-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DAINIPPON INK & CHEMICALS (JP) 2019-03-27 EP disclosed
US-10174254-B2 Nematic liquid crystal composition and liquid crystal display element using the same DIC CORPORATION (JP) 2019-01-08 US disclosed
US-20180163134-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2018-06-14 US disclosed
WO-2018104285-A2 ADDITIVES FOR LIQUID CRYSTAL MIXTURES MERCK PATENT GMBH (DE) 2018-06-14 WO disclosed
EP-2735600-B1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DAINIPPON INK & CHEMICALS (JP) 2018-01-17 EP disclosed
US-20170260451-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2017-09-14 US disclosed
US-9624434-B2 Nematic liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2017-04-18 US disclosed
US-20170029698-A1 ANTIOXIDANT FOR LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE USING LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2017-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10759997-B2 Polymerizable compound, liquid crystal medium containing same and liquid crystal display device BPHL, KLK3, NEFM SLC6A2 3142/4885SLC6A4 2425/4885SLC6A3 2599/4885
US-20170029698-A1 ANTIOXIDANT FOR LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE USING LIQUID CRYSTAL COMPOSITION GPX1, LPO, SCO2 SLC6A2 2770/4885SLC6A4 4137/4885SLC6A3 2806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.