SCHEMBL18459293

SCHEMBL18459293

CCC(C)c1cc(CN)cc(CN)c1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
USP2 O75604 1/20 0.41
GAA P10253 1/20 0.41
PKM P14618 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41
HDAC4 P56524 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
TAAR1 Q96RJ0 2/20 0.32
CSNK2A1 P68400 2/20 0.32
SLC7A5 Q01650 1/20 0.31
TSHR P16473 3/20 0.31
CYP2C9 P11712 1/20 0.31
SCN10A Q9Y5Y9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14298919 0.79 HDAC4 (0.50) ALDH1A1USP2GAAPKMHPGD
SCHEMBL25802780 0.79 ADRA2A (0.35) HDAC8
SCHEMBL12014104 0.78 IDO1 (0.37) ALDH1A1GAATAAR1CSNK2A1
SCHEMBL24246248 0.77 ALDH1A1 (0.46) ALDH1A1USP2GAAPKMHPGD
SCHEMBL394465 0.77 ALDH1A1 (0.46) ALDH1A1USP2GAAPKMHPGD
SCHEMBL14644326 0.77 ALDH1A1 (0.46) ALDH1A1USP2GAAPKMHPGD
SCHEMBL11686432 0.77 ALDH1A1 (0.46) ALDH1A1USP2GAAPKMHPGD
Hydrochloric Acid SCHEMBL4985421 0.76 ALDH1A1 (0.44) ALDH1A1USP2GAAPKMHPGD
SCHEMBL15249714 0.76 PLG (0.33) TAAR1CSNK2A1
SCHEMBL10178780 0.74 USP2 (0.39) ALDH1A1USP2GAAPKMHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9701628-B2 12-epi pleuromutilins NABRIVA THERAPEUTICS AG (AT) 2017-07-11 US disclosed
WO-2016122887-A9 OLIGOSACCHARIDE COMPOSITIONS FOR USE ANIMAL FEED AND METHODS OF PRODUCING THEREOF MIDORI USA, INC. (US) 2017-02-02 WO disclosed