Menadione

Menadione

SCHEMBL1846014

CC1=CC(=O)c2ccccc2C1=O.N.O=S(O)O

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.78
MAPT P10636 5/20 0.78
CDC25A P30304 4/20 0.78
CDC25B P30305 4/20 0.78
HPGD P15428 4/20 0.78
MAPK1 P28482 4/20 0.78
IDO1 P14902 3/20 0.78
CYP3A4 P08684 3/20 0.78
MEN1 O00255 3/20 0.78
KMT2A Q03164 3/20 0.78
LMNA P02545 3/20 0.78
TP53 P04637 2/20 0.78
CYP1A2 P05177 2/20 0.78
HSPD1 P10809 2/20 0.78
BLM P54132 2/20 0.78
HSPE1 P61604 2/20 0.78
SMN1; SMN2 Q16637 2/20 0.78
TST Q16762 2/20 0.78
GAA P10253 2/20 0.78
ATM Q13315 2/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Menadione SCHEMBL433363 0.98 ALDH1A1 (0.81) ALDH1A1MAPTCDC25ACDC25BHPGD
Menadione SCHEMBL6675827 0.96 ALDH1A1 (0.78) ALDH1A1MAPTCDC25ACDC25BHPGD
Menadione SCHEMBL9807661 0.90 MAPT (0.95) ALDH1A1MAPTCDC25ACDC25BHPGD
Menadione SCHEMBL30514399 0.89 ALDH1A1 (0.72) ALDH1A1MAPTCDC25ACDC25BHPGD
Menadione SCHEMBL207465 0.89 ALDH1A1 (0.72) ALDH1A1MAPTCDC25ACDC25BHPGD
Menadione SCHEMBL27738127 0.89 ALDH1A1 (0.66) ALDH1A1MAPTCDC25ACDC25BHPGD
Menadione SCHEMBL29351164 0.88 MAPT (1.00) ALDH1A1MAPTCDC25ACDC25BHPGD
Menadione SCHEMBL25970 0.88 MAPT (1.00) ALDH1A1MAPTCDC25ACDC25BHPGD
Menadione SCHEMBL1364028 0.88 MAPT (1.00) ALDH1A1MAPTCDC25ACDC25BHPGD
Menadione SCHEMBL19356853 0.88 MAPT (1.00) ALDH1A1MAPTCDC25ACDC25BHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023175045-A1 PROCEDURE FOR THE USE OF MENADIONE FOR THE CONTROL OF A NEW TROPICAL RACE OF FUSARIUM ODORATISSIMUM (TR4) IN PLANTS CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) 2023-09-21 WO claimed
EP-2324709-A1 USE OF MENADIONE TO INCREASE SALINE STRESS TOLERANCE IN PLANTS Consejo Superior de Investigaciones Científicas (CSIC) (ES) 2011-05-25 EP claimed
US-9481612-B2 Root-growth-promoting liquid formulation that enhances defense response in plants, and use of same AGRO STOCK S.A. (ES) 2016-11-01 US disclosed
US-20150246853-A1 ROOT-GROWTH-PROMOTING LIQUID FORMULATION THAT ENHANCES DEFENCE RESPONSE IN PLANTS, AND USE OF SAME AGRO STOCK S.A. (ES) 2015-09-03 US disclosed
EP-2862443-A1 ROOT-GROWTH-PROMOTING LIQUID FORMULATION THAT ENHANCES DEFENCE RESPONSE IN PLANTS, AND USE OF SAME AGRO Stock S.A. (ES) 2015-04-22 EP disclosed
EP-2324709-A1 USE OF MENADIONE TO INCREASE SALINE STRESS TOLERANCE IN PLANTS Consejo Superior de Investigaciones Científicas (CSIC) (ES) 2011-05-25 EP disclosed