Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254957 | 0.84 | MAPT (0.56) | MAPTEPHX2GPR3L3MBTL1KDM4E | |
| SCHEMBL147828 | 0.81 | CA2 (0.52) | MAPTEPHX2L3MBTL1KDM4ETSHR | |
| SCHEMBL22816206 | 0.79 | MAPT (0.42) | MAPTEPHX2L3MBTL1KDM4EKIF11 | |
| SCHEMBL17018203 | 0.78 | MAPT (0.44) | MAPTEPHX2L3MBTL1KDM4EKIF11 | |
| SCHEMBL14986106 | 0.78 | MAPT (0.40) | MAPTEPHX2GPR3L3MBTL1KDM4E | |
| SCHEMBL1393204 | 0.76 | CA1 (0.59) | MAPTEPHX2L3MBTL1KDM4ESCN5A | |
| SCHEMBL12874094 | 0.76 | EPHX2 (0.43) | MAPTEPHX2GPR3L3MBTL1KIF11 | |
| SCHEMBL6610143 | 0.76 | CA1 (0.48) | MAPTEPHX2KIF11NISCHSCN5A | |
| SCHEMBL28780452 | 0.76 | EPHX2 (0.50) | MAPTEPHX2GPR3L3MBTL1KDM4E | |
| SCHEMBL3336949 | 0.75 | GPR3 (0.47) | MAPTEPHX2GPR3L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1935922-B1 | Method for manufacturing SiOC-linked, linear polydimethyl siloxane polyoxyalkyl block copolymers and their application | EVONIK GOLDSCHMIDT GMBH (DE) | 2013-05-08 | — | — | EP | claimed |
| EP-1935920-B1 | Method for converting polyorganosiloxanes and their application | EVONIK GOLDSCHMIDT GMBH (DE) | 2011-11-02 | — | — | EP | claimed |
| US-7825205-B2 | Process for the preparation of SiOC-linked, linear polydimethylsiloxane-polyoxyalkylene block copolymers and their use | EVONIK GOLDSCHMIDT GMBH (DE) | 2010-11-02 | — | — | US | claimed |
| US-7825206-B2 | Process for reacting polyorganosiloxanes and their use | EVONIK GOLDSCHMIDT GMBH (DE) | 2010-11-02 | — | — | US | claimed |
| EP-1544232-B1 | Polysiloxanes with SiOC-bounded (meth)acrylic acid ester groups, process for their preparation and their use as irradiation-curable release coating | EVONIK GOLDSCHMIDT GMBH (DE) | 2010-03-03 | — | — | EP | claimed |
| US-20080153992-A1 | Process for the preparation of SiOC-linked, linear polydimethylsiloxane-polyoxyalkylene block copolymers and their use | EVONIK GOLDSCHMIDT GMBH (DE) | 2008-06-26 | — | — | US | claimed |
| US-20080153934-A1 | Process for reacting polyorganosiloxanes and their use | EVONIK GOLDSCHMIDT GMBH (DE) | 2008-06-26 | — | — | US | claimed |
| EP-1935922-A2 | Method for manufacturing SiOC-linked, linear polydimethyl siloxane polyoxyalkyl block copolymers and their application | Evonik Goldschmidt GmbH (DE) | 2008-06-25 | — | — | EP | claimed |
| EP-1935920-A2 | Method for converting polyorganosiloxanes and their application | Evonik Goldschmidt GmbH (DE) | 2008-06-25 | — | — | EP | claimed |
| US-20070299231-A1 | POLYSILOXANES CONTAINING (METH)ACRYLIC ESTER GROUPS ATTACHED VIA SiOC GROUPS, PROCESSES FOR PREPARING THEM AND THEIR USE AS A RADIATION-CURABLE ADHESIVE COATING | GOLDSCHMIDT GMBH (DE) | 2007-12-27 | — | — | US | claimed |
| EP-1460099-B1 | Process for modifying polysiloxanes | GOLDSCHMIDT GMBH (DE) | 2006-06-21 | — | — | EP | claimed |
| US-20060041097-A1 | Catalytic system for the dehydrogenative condensation of polyorganosiloxanes with alcohols and a process for preparing organically modified polyorganosiloxanes | EVONIK DEGUSSA GMBH (DE) | 2006-02-23 | — | — | US | claimed |
| EP-1627892-A1 | Catalytic system for the dehyrogenative condensation of polyorganosiloxanes with alcohols and process for the preparation of organically modified polyorganosiloxanes | Goldschmidt GmbH (DE) | 2006-02-22 | — | — | EP | claimed |
| US-20050136269-A1 | Polysiloxanes containing (meth)acrylic ester groups attached via SiOC groups, processes for preparing them and their use as a radiation-curable abhesive coating | EVONIK GOLDSCHMIDT GMBH (DE) | 2005-06-23 | — | — | US | claimed |
| EP-1544232-A1 | Polysiloxanes with SiOC-bounded (meth)acrylic acid ester groups, process for their preparation and their use as irradiation-curable release coating | Goldschmidt GmbH (DE) | 2005-06-22 | — | — | EP | claimed |
| US-20040186260-A1 | Process for the reaction of polyorganosiloxanes | GOLDSCHMIDT GMBH (DE) | 2004-09-23 | — | — | US | claimed |
| EP-1460099-A1 | Process for modifying polysiloxanes | Goldschmidt AG (DE) | 2004-09-22 | — | — | EP | claimed |
| EP-4594394-A1 | METHOD FOR PRODUCING SIOC-LINKED, LINEAR POLYDIALKYLSILOXANE-POLYETHER BLOCK COPOLYMERS AND THE USE THEREOF | Evonik Operations GmbH (DE) | 2025-08-06 | — | — | EP | disclosed |
| US-20040186260-A1 | Process for the reaction of polyorganosiloxanes | GOLDSCHMIDT GMBH (DE) | 2004-09-23 | — | — | US | disclosed |
| EP-1460099-A1 | Process for modifying polysiloxanes | Goldschmidt AG (DE) | 2004-09-22 | — | — | EP | disclosed |