Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18463879 | 0.89 | BACE1 (0.44) | BACE1ALDH1A1SMN1; SMN2ABCG2CYP1A2 | |
| SCHEMBL263666 | 0.81 | BACE1 (0.50) | BACE1ALDH1A1SMN1; SMN2HDAC1HDAC2 | |
| SCHEMBL27887111 | 0.81 | BACE1 (0.46) | BACE1ALDH1A1SMN1; SMN2HDAC1HDAC2 | |
| SCHEMBL1294236 | 0.80 | ALDH1A1 (0.48) | BACE1ALDH1A1SMN1; SMN2HDAC1HDAC2 | |
| SCHEMBL18463872 | 0.78 | ALDH1A1 (0.37) | BACE1ALDH1A1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL7602003 | 0.75 | BACE1 (0.47) | BACE1ALDH1A1SMN1; SMN2HDAC1HDAC2 | |
| SCHEMBL262639 | 0.75 | BACE1 (0.50) | BACE1ALDH1A1SMN1; SMN2HDAC1HDAC2 | |
| SCHEMBL2001591 | 0.74 | ALDH1A1 (0.65) | BACE1ALDH1A1SMN1; SMN2ABCG2CYP1A2 | |
| SCHEMBL1000331 | 0.73 | MGAM (0.56) | BACE1ALDH1A1SMN1; SMN2HDAC1HDAC2 | |
| SCHEMBL1293647 | 0.72 | BACE1 (0.47) | BACE1ALDH1A1SMN1; SMN2HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170029372-A1 | BINDING FUNCTION 3 (BF3) SITE COMPOUNDS AS THERAPEUTICS AND METHODS FOR THEIR USE | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2017-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170029372-A1 | BINDING FUNCTION 3 (BF3) SITE COMPOUNDS AS THERAPEUTICS AND METHODS FOR THEIR USE | KLK3, SHBG, ACP3 | BACE1 1738/4885ALDH1A1 2387/4885SMN1; SMN2 3028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.