Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18463765 | 0.83 | PABPC1 (0.39) | ALDH1A1SMN1; SMN2PABPC1HTTCYP1A2 | |
| SCHEMBL27944508 | 0.82 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2PABPC1HTTCYP1A2 | |
| SCHEMBL18464470 | 0.82 | KDM4E (0.40) | ALDH1A1HPGDALOX15HSD17B10MAPK1 | |
| SCHEMBL1293884 | 0.81 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2PABPC1HTTCYP1A2 | |
| SCHEMBL18463879 | 0.80 | BACE1 (0.44) | ALDH1A1SMN1; SMN2PABPC1HTTCYP1A2 | |
| SCHEMBL18464545 | 0.78 | BACE1 (0.46) | ALDH1A1SMN1; SMN2HTTCYP1A2CYP2C19 | |
| SCHEMBL2621767 | 0.76 | CSF1R (0.42) | ALDH1A1SMN1; SMN2PABPC1HTTCYP1A2 | |
| SCHEMBL2000194 | 0.75 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2HTTCYP1A2RXFP1 | |
| SCHEMBL13905401 | 0.74 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2PABPC1HTTRXFP1 | |
| SCHEMBL1293449 | 0.74 | GSK3B (0.41) | ALDH1A1SMN1; SMN2PABPC1HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170029372-A1 | BINDING FUNCTION 3 (BF3) SITE COMPOUNDS AS THERAPEUTICS AND METHODS FOR THEIR USE | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2017-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170029372-A1 | BINDING FUNCTION 3 (BF3) SITE COMPOUNDS AS THERAPEUTICS AND METHODS FOR THEIR USE | KLK3, SHBG, ACP3 | ALDH1A1 2387/4885SMN1; SMN2 3028/4885PABPC1 734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.