Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 8/20 | 0.43 |
| ▸ | NPY1R | P25929 | 7/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.43 |
| ▸ | NPY2R | P49146 | 4/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26017775 | 0.90 | KMT2A (0.47) | NPY4RNPY1RNPY5RNPY2RC3AR1 | |
| SCHEMBL27846680 | 0.87 | NPY4R (0.42) | NPY4RNPY1RNPY5RNPY2RHDAC2 | |
| SCHEMBL9207685 | 0.86 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2RHDAC2 | |
| SCHEMBL9207694 | 0.86 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2RHDAC2 | |
| Hydrochloric Acid SCHEMBL8830966 | 0.85 | NOD1 (0.48) | NPY4RNPY1RNPY5RNPY2RHDAC2 | |
| SCHEMBL18796580 | 0.85 | NOD1 (0.51) | NPY4RNPY1RNPY5RNPY2RKMT2A | |
| SCHEMBL18991155 | 0.85 | NOD1 (0.51) | NPY4RNPY1RNPY5RNPY2RKMT2A | |
| SCHEMBL28263952 | 0.85 | NOD1 (0.51) | NPY4RNPY1RNPY5RNPY2RKMT2A | |
| SCHEMBL1541966 | 0.85 | NOD1 (0.51) | NPY4RNPY1RNPY5RNPY2RKMT2A | |
| SCHEMBL27805202 | 0.85 | NOD1 (0.51) | NPY4RNPY1RNPY5RNPY2RKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170029381-A1 | TETRAHYDRO-BENZOIMIDAZOLYL MODULATORS OF TGR5 | JANSSEN PHARMACEUTICA NV (BE) | 2017-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170029381-A1 | TETRAHYDRO-BENZOIMIDAZOLYL MODULATORS OF TGR5 | GLRA1, GRM5, TRHR | NPY4R 34/4885NPY1R 21/4885NPY5R 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.