Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 12/20 | 0.42 |
| ▸ | NPY1R | P25929 | 8/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.37 |
| ▸ | NPY2R | P49146 | 5/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18465137 | 0.87 | NPY4R (0.43) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL5807981 | 0.87 | NPY4R (0.44) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL2390736 | 0.87 | NPY4R (0.44) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL13950273 | 0.86 | NPY4R (0.35) | NPY4RNPY1RNPY5RNPY2RC3AR1 | |
| Hydrochloric Acid SCHEMBL11506342 | 0.86 | NPY4R (0.44) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL9207685 | 0.85 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL9207694 | 0.85 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL21879809 | 0.84 | NPY4R (0.44) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL26962723 | 0.82 | NPY4R (0.42) | NPY4RNPY1RNPY5RNPY2RFOLH1 | |
| SCHEMBL17015152 | 0.82 | NPY4R (0.50) | NPY4RNPY1RNPY5RNPY2RFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101906069-B | (S)-2-substituted-(3'-acetyl-2'-pyridone-1'-yl) acetic acid as well as preparation method and application thereof | UNIV CAPITAL MEDICAL | 2012-12-12 | — | — | CN | disclosed |
| CN-101906069-A | (S)-2-substituted-(3'-acetyl-2'-pyridone-1'-yl) acetic acid as well as preparation method and application thereof | UNIV CAPITAL MEDICAL | 2010-12-08 | — | — | CN | disclosed |