SCHEMBL184705

SCHEMBL184705

CCOC(=O)Cc1ccc(S)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4Z1 Q86W10 1/20 0.54
MAPT P10636 2/20 0.51
LMNA P02545 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
CYP4F2 P78329 2/20 0.47
CYP4A11 Q02928 2/20 0.47
ALDH1A1 P00352 2/20 0.46
KDM4E B2RXH2 1/20 0.46
TSHR P16473 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TBXAS1 P24557 1/20 0.45
LIPE Q05469 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
MAPK1 P28482 1/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
PAM P19021 1/20 0.43
NPC1 O15118 1/20 0.43
PKM P14618 1/20 0.43
NFKB1 P19838 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68851 0.90 CYP4Z1 (0.62) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2
SCHEMBL1809809 0.85 CYP4Z1 (0.54) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2
SCHEMBL6057577 0.84 CYP4F2 (0.59) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2
SCHEMBL68930 0.84 CYP4Z1 (0.57) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2
SCHEMBL1107146 0.84 CYP4Z1 (0.57) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2
SCHEMBL10299459 0.84 CYP4Z1 (0.57) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2
SCHEMBL6207253 0.82 CYP4Z1 (0.55) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2
SCHEMBL5545889 0.82 CYP4Z1 (0.55) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2
SCHEMBL18932531 0.82 CYP4Z1 (0.55) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2
SCHEMBL5034285 0.82 CYP4Z1 (0.59) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118561858-A High water-solubility phthalocyanine modified by amine oxide group, preparation and application thereof 福州大学 2024-08-30 CN claimed
CN-118258802-A Quick detection method for qualitative and quantitative pathogenic microorganisms 北京数字天眼生物科技有限公司 2024-06-28 CN claimed
CN-109807323-B Silver cube/flower-shaped silicon dioxide core-shell nano material and preparation method and application thereof 宁波工程学院 2021-03-02 CN claimed
CN-109807323-A A kind of silver cube/flower-shaped silica core shell nanometer material and its preparation method and application 宁波工程学院 2019-05-28 CN claimed
CN-119823008-A Preparation method of 4-methylsulfonyl phenylacetic acid 浙江东亚药业股份有限公司 2025-04-15 CN disclosed
CN-118561858-A High water-solubility phthalocyanine modified by amine oxide group, preparation and application thereof 福州大学 2024-08-30 CN disclosed
CN-118258802-A Quick detection method for qualitative and quantitative pathogenic microorganisms 北京数字天眼生物科技有限公司 2024-06-28 CN disclosed
CN-118258802-A Quick detection method for qualitative and quantitative pathogenic microorganisms 北京数字天眼生物科技有限公司 2024-06-28 CN disclosed
CN-108430973-B ROR gamma modulators 领先制药控股公司 2021-09-21 CN disclosed
CN-108473430-B ROR gamma modulators 领先制药控股公司 2021-05-25 CN disclosed
CN-109807323-B Silver cube/flower-shaped silicon dioxide core-shell nano material and preparation method and application thereof 宁波工程学院 2021-03-02 CN disclosed
CN-109807323-B Silver cube/flower-shaped silicon dioxide core-shell nano material and preparation method and application thereof 宁波工程学院 2021-03-02 CN disclosed
US-5962695-A ANTICOAGULANT DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1999-10-05 US disclosed
US-5866577-A AN ANTICOAGULANT AGENT DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1999-02-02 US disclosed
US-5620991-A ANTICOAGULANTS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1997-04-15 US disclosed
US-5576343-A ANTICOAGULANTS; BLOOD-COAGULATION FACTOR X INHIBITORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1996-11-19 US disclosed
EP-0540051-B1 Aromatic amidine derivatives and salts thereof DAIICHI SEIYAKU CO (JP) 1996-04-03 EP disclosed
EP-0540051-A1 Aromatic amidine derivatives and salts thereof DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1993-05-05 EP disclosed
US-3956345-A POLYESTER CIBA-GEIGY AG (CH) 1976-05-11 US disclosed
US-3946036-A 6,11-Dihydro-11-oxo-dibenzo[b,e]thiepine-2-acetic acids SANDOZ LTD. (CH) 1976-03-23 US disclosed