Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | UGT2B7 | P16662 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18472127 | 1.00 | EPHX2 (0.37) | EPHX2UGT2B7ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL956616 | 0.89 | UGT2B7 (0.36) | UGT2B7MEN1KMT2A | |
| SCHEMBL18465429 | 0.89 | EPHX2 (0.37) | EPHX2UGT2B7 | |
| SCHEMBL18472112 | 0.89 | EPHX2 (0.37) | EPHX2UGT2B7 | |
| SCHEMBL956614 | 0.89 | UGT2B7 (0.36) | UGT2B7MEN1KMT2A | |
| SCHEMBL18472109 | 0.89 | EPHX2 (0.37) | EPHX2UGT2B7 | |
| SCHEMBL18472125 | 0.89 | EPHX2 (0.37) | EPHX2UGT2B7 | |
| SCHEMBL958792 | 0.89 | UGT2B7 (0.36) | UGT2B7MEN1KMT2A | |
| SCHEMBL958793 | 0.89 | UGT2B7 (0.36) | UGT2B7MEN1KMT2A | |
| SCHEMBL18472121 | 0.89 | EPHX2 (0.37) | EPHX2UGT2B7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170037018-A1 | Opsin-Binding Ligands, Compositions and Methods of Use | BIKAM PHARMACEUTICALS INC. (US) | 2017-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037018-A1 | Opsin-Binding Ligands, Compositions and Methods of Use | CRYAB, CRYAA, UACA | EPHX2 3970/4885UGT2B7 3213/4885ALDH1A1 2958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.