Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 15/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16559840 | 0.89 | POLB (0.40) | POLBAPEX1HTTTDP1FFAR4 | |
| SCHEMBL22845690 | 0.88 | POLB (0.41) | POLBAPEX1HTTTDP1FFAR4 | |
| SCHEMBL25795370 | 0.87 | POLB (0.37) | POLBAPEX1HTTTDP1FFAR4 | |
| SCHEMBL18509368 | 0.87 | THRB (0.35) | POLBAPEX1HTTTDP1FFAR4 | |
| SCHEMBL17538614 | 0.86 | POLB (0.43) | POLBAPEX1HTTTDP1FFAR4 | |
| SCHEMBL25945144 | 0.85 | POLB (0.36) | POLBAPEX1HTTTDP1FFAR4 | |
| SCHEMBL19158978 | 0.85 | FFAR1 (0.40) | POLBAPEX1HTTTDP1FFAR4 | |
| SCHEMBL22023580 | 0.84 | POLB (0.37) | POLBAPEX1HTTTDP1FFAR4 | |
| SCHEMBL20275212 | 0.84 | POLB (0.36) | POLBAPEX1HTTTDP1FFAR4 | |
| SCHEMBL16573113 | 0.84 | POLB (0.45) | POLBAPEX1HTTTDP1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3263673-B1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-10-02 | — | — | EP | disclosed |
| WO-2017020998-A1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2017-02-09 | — | — | WO | disclosed |