Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22845690 | 0.93 | POLB (0.41) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL18688195 | 0.83 | POLB (0.41) | POLBAPEX1HTTTDP1CYP11B1 | |
| SCHEMBL21693482 | 0.82 | POLB (0.40) | POLBAPEX1HTTTDP1CYP11B1 | |
| SCHEMBL18511121 | 0.82 | POLB (0.38) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL18476298 | 0.82 | POLB (0.37) | POLBAPEX1HTTTDP1 | |
| SCHEMBL16559838 | 0.80 | POLB (0.44) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL22592264 | 0.79 | POLB (0.39) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL19559099 | 0.79 | POLB (0.39) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL24440871 | 0.79 | POLB (0.43) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL21289112 | 0.79 | POLB (0.43) | THRBPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017020998-A1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2017-02-09 | — | — | WO | disclosed |